TY - JOUR
T1 - In-hospital mortality and failure to rescue after cytoreductive nephrectomy
AU - Trinh, Quoc Dien
AU - Bianchi, Marco
AU - Hansen, Jens
AU - Tian, Zhe
AU - Abdollah, Firas
AU - Shariat, Shahrokh F.
AU - Montorsi, Francesco
AU - Perrotte, Paul
AU - Karakiewicz, Pierre I.
AU - Sun, Maxine
PY - 2013/6
Y1 - 2013/6
N2 - Background: The risk of in-hospital mortality after cytoreductive nephrectomy (CNT) is non-negligible and may vary widely according to various patient and hospital characteristics and clinical contexts. Objective: To better elucidate the mechanisms underlying variability in operative mortality after CNT. Design, setting, and patients: Using the US-based Nationwide Inpatient Sample registry, a weighted estimate of 16 285 patients with metastatic renal cell carcinoma (mRCC) treated with CNT between 1998 and 2007 was made retrospectively. Outcome measurements and statistical analysis: Failure to rescue (FTR), defined as the number of deaths in patients who developed an adverse outcome during hospitalization. Univariable and multivariable logistic regression models were used. Results: Of all 16 285 mRCC patients who underwent a CNT, 31% had an occurrence of one complication or more. The overall FTR rate was 5% and differed significantly according to age (≥75 yr vs
AB - Background: The risk of in-hospital mortality after cytoreductive nephrectomy (CNT) is non-negligible and may vary widely according to various patient and hospital characteristics and clinical contexts. Objective: To better elucidate the mechanisms underlying variability in operative mortality after CNT. Design, setting, and patients: Using the US-based Nationwide Inpatient Sample registry, a weighted estimate of 16 285 patients with metastatic renal cell carcinoma (mRCC) treated with CNT between 1998 and 2007 was made retrospectively. Outcome measurements and statistical analysis: Failure to rescue (FTR), defined as the number of deaths in patients who developed an adverse outcome during hospitalization. Univariable and multivariable logistic regression models were used. Results: Of all 16 285 mRCC patients who underwent a CNT, 31% had an occurrence of one complication or more. The overall FTR rate was 5% and differed significantly according to age (≥75 yr vs
KW - Cytoreductive nephrectomy
KW - In-hospital mortality
KW - Metastatic renal cell carcinoma
KW - Morbidity
UR - http://www.scopus.com/inward/record.url?scp=84876463221&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84876463221&partnerID=8YFLogxK
U2 - 10.1016/j.eururo.2012.08.069
DO - 10.1016/j.eururo.2012.08.069
M3 - Article
C2 - 22981674
AN - SCOPUS:84876463221
SN - 0302-2838
VL - 63
SP - 1107
EP - 1114
JO - European Urology
JF - European Urology
IS - 6
ER -