TY - JOUR
T1 - Impulse control disorders in Parkinson's disease A systematic review on risk factors and pathophysiology
AU - Latella, Desiree
AU - Maggio, Maria Grazia
AU - Maresca, Giuseppa
AU - Saporoso, Anna Federica
AU - Le Cause, Maria
AU - Manuli, Alfredo
AU - Milardi, Demetrio
AU - Bramanti, Placido
AU - De Luca, Rosaria
AU - Calabrò, Rocco Salvatore
PY - 2019/3/15
Y1 - 2019/3/15
N2 - Aim: Purpose of this review is to evaluate the potential risk factors that may predispose to the development of Impulse control disorders (ICDs) in Parkinson's Disease (PD) patients, including the effects of dopaminergic therapy. Methods: This descriptive review was conducted to identificate risk factors that could cause impulsive control disorders in PD. Studies were found on PubMed (2010–2018), Web Of Science (January 2010–July 2018) and Cochrane (2010–2018) databases. Results: The data suggest that intrinsic and extrinsic factors may be involved in the development of behavioral complications. To date, the link between PD and the development of ICDs is not very clear, but studies highlight the existence of a predisposition to ICDs in the presence of risk factors. Conclusions: A better assessment of the behavioral disorders of PD may be useful in the rehabilitative intervention for increasing the quality of life.
AB - Aim: Purpose of this review is to evaluate the potential risk factors that may predispose to the development of Impulse control disorders (ICDs) in Parkinson's Disease (PD) patients, including the effects of dopaminergic therapy. Methods: This descriptive review was conducted to identificate risk factors that could cause impulsive control disorders in PD. Studies were found on PubMed (2010–2018), Web Of Science (January 2010–July 2018) and Cochrane (2010–2018) databases. Results: The data suggest that intrinsic and extrinsic factors may be involved in the development of behavioral complications. To date, the link between PD and the development of ICDs is not very clear, but studies highlight the existence of a predisposition to ICDs in the presence of risk factors. Conclusions: A better assessment of the behavioral disorders of PD may be useful in the rehabilitative intervention for increasing the quality of life.
KW - Binge eating
KW - Gambling
KW - Hypersexuality
KW - Neurodegenerative disorders
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U2 - 10.1016/j.jns.2019.01.034
DO - 10.1016/j.jns.2019.01.034
M3 - Review article
C2 - 30690412
AN - SCOPUS:85060454212
SN - 0022-510X
VL - 398
SP - 101
EP - 106
JO - Journal of the Neurological Sciences
JF - Journal of the Neurological Sciences
ER -