Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)

G. G. Garzetti; M. Cignitti; F. Marchegiani; M. Provinciali; A. M. Z aia; N. Fabris; C. Pieri; C. Romanini

Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)

G. G. Garzetti, M. Cignitti, F. Marchegiani, M. Provinciali, A. M. Z aia, N. Fabris, C. Pieri, C. Romanini

Istituto Nazionale di Riposo e Cura per Anziani V.E. II

Research output: Contribution to journal › Article › peer-review

Abstract

In the present study we observed the absolute number of NK cells and the NK activity in 10 patients with cervical cancer. NK activity was determined before and after stimulation with Active Lipids. We reported a significant decrease of basal NK activity, but after AL stimulation NK activity was increased with statistical significance. Therefore our findings show that the reduction of NK activity in neoplastic patients is not an irreversible phenomenon since it can be restored by 'in vitro' AL administration. This is important for the adoptive immunotherapy by which we could give LAK cells to the patients.

Original language	English
Pages (from-to)	123-125
Number of pages	3
Journal	European Journal of Gynaecological Oncology
Volume	11
Issue number	2
Publication status	Published - 1990

ASJC Scopus subject areas

Obstetrics and Gynaecology
Oncology

Cite this

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title = "Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)",

abstract = "In the present study we observed the absolute number of NK cells and the NK activity in 10 patients with cervical cancer. NK activity was determined before and after stimulation with Active Lipids. We reported a significant decrease of basal NK activity, but after AL stimulation NK activity was increased with statistical significance. Therefore our findings show that the reduction of NK activity in neoplastic patients is not an irreversible phenomenon since it can be restored by 'in vitro' AL administration. This is important for the adoptive immunotherapy by which we could give LAK cells to the patients.",

author = "Garzetti, {G. G.} and M. Cignitti and F. Marchegiani and M. Provinciali and {Z aia}, {A. M.} and N. Fabris and C. Pieri and C. Romanini",

year = "1990",

language = "English",

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T1 - Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)

AU - Garzetti, G. G.

AU - Cignitti, M.

AU - Marchegiani, F.

AU - Provinciali, M.

AU - Z aia, A. M.

AU - Fabris, N.

AU - Pieri, C.

AU - Romanini, C.

PY - 1990

Y1 - 1990

N2 - In the present study we observed the absolute number of NK cells and the NK activity in 10 patients with cervical cancer. NK activity was determined before and after stimulation with Active Lipids. We reported a significant decrease of basal NK activity, but after AL stimulation NK activity was increased with statistical significance. Therefore our findings show that the reduction of NK activity in neoplastic patients is not an irreversible phenomenon since it can be restored by 'in vitro' AL administration. This is important for the adoptive immunotherapy by which we could give LAK cells to the patients.

AB - In the present study we observed the absolute number of NK cells and the NK activity in 10 patients with cervical cancer. NK activity was determined before and after stimulation with Active Lipids. We reported a significant decrease of basal NK activity, but after AL stimulation NK activity was increased with statistical significance. Therefore our findings show that the reduction of NK activity in neoplastic patients is not an irreversible phenomenon since it can be restored by 'in vitro' AL administration. This is important for the adoptive immunotherapy by which we could give LAK cells to the patients.

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JO - European Journal of Gynaecological Oncology

JF - European Journal of Gynaecological Oncology

IS - 2

ER -

Improvement of decreased natural killer cell activity in cervical cancer patients by active lipids (AL 721)

Abstract

ASJC Scopus subject areas

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