TY - JOUR
T1 - Impact of personalized diet and probiotic supplementation on inflammation, nutritional parameters and intestinal microbiota - The "RISTOMED project"
T2 - Randomized controlled trial in healthy older people
AU - Valentini, Luzia
AU - Pinto, Alessandro
AU - Bourdel-Marchasson, Isabelle
AU - Ostan, Rita
AU - Brigidi, Patrizia
AU - Turroni, Silvia
AU - Hrelia, Silvana
AU - Hrelia, Patrizia
AU - Bereswill, Stefan
AU - Fischer, André
AU - Leoncini, Emanuela
AU - Malaguti, Marco
AU - Blanc-Bisson, Christéle
AU - Durrieu, Jessica
AU - Spazzafumo, Liana
AU - Buccolini, Fabio
AU - Pryen, Florence
AU - Donini, Lorenzo Maria
AU - Franceschi, Claudio
AU - Lochs, Herbert
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Objectives: To assess the impact of a personalized diet, with or without addition of VSL#3 preparation, on biomarkers of inflammation, nutrition, oxidative stress and intestinal microbiota in 62 healthy persons aged 65-85 years. Design: Open label, randomized, multicenter study. Primary endpoint: High-sensitivity C-reactive protein. Setting: Community. Interventions: Eight week web-based dietary advice (RISTOMED platform) alone or with supplementation of VSL#3 (2 capsules per day). The RISTOMED diet was optimized to reduce inflammation and oxidative stress. Measurements: Blood and stool samples were collected on days 1 and 56. Results: Dietalone reduced ESR (. p=0.02), plasma levels of cholesterol (. p
AB - Objectives: To assess the impact of a personalized diet, with or without addition of VSL#3 preparation, on biomarkers of inflammation, nutrition, oxidative stress and intestinal microbiota in 62 healthy persons aged 65-85 years. Design: Open label, randomized, multicenter study. Primary endpoint: High-sensitivity C-reactive protein. Setting: Community. Interventions: Eight week web-based dietary advice (RISTOMED platform) alone or with supplementation of VSL#3 (2 capsules per day). The RISTOMED diet was optimized to reduce inflammation and oxidative stress. Measurements: Blood and stool samples were collected on days 1 and 56. Results: Dietalone reduced ESR (. p=0.02), plasma levels of cholesterol (. p
KW - Aging
KW - Inflammation
KW - Internet
KW - Nutritional software
KW - Oxidative stress
KW - VSL#3
UR - http://www.scopus.com/inward/record.url?scp=84930703126&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84930703126&partnerID=8YFLogxK
U2 - 10.1016/j.clnu.2014.09.023
DO - 10.1016/j.clnu.2014.09.023
M3 - Article
C2 - 25453395
AN - SCOPUS:84930703126
SN - 0261-5614
VL - 34
SP - 593
EP - 602
JO - Clinical Nutrition
JF - Clinical Nutrition
IS - 4
ER -