Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome

Sara D'Imperio, Michelle M Monasky, Emanuele Micaglio, Gabriele Negro, Carlo Pappone

Research output: Contribution to journalReview articlepeer-review


A healthy regime is fundamental for the prevention of cardiovascular diseases (CVD). In inherited channelopathies, such as Brugada syndrome (BrS) and Long QT syndrome (LQTS), unfortunately, sudden cardiac death could be the first sign for patients affected by these syndromes. Several known factors are used to stratify the risk of developing cardiac arrhythmias, although none are determinative. The risk factors can be affected by adjusting lifestyle habits, such as a particular diet, impacting the risk of arrhythmogenic events and mortality. To date, the importance of understanding the relationship between diet and inherited channelopathies has been underrated. Therefore, we describe herein the effects of dietary factors on the development of arrhythmia in patients affected by BrS and LQTS. Modifying the diet might not be enough to fully prevent arrhythmias, but it can help lower the risk.

Original languageEnglish
Issue number8
Publication statusPublished - Jul 21 2021


  • Alcohol Drinking
  • Animals
  • Brugada Syndrome/complications
  • Death, Sudden, Cardiac/etiology
  • Diet
  • Diet, Ketogenic/adverse effects
  • Eating
  • Electrocardiography
  • Fatty Acids, Omega-3/administration & dosage
  • Food
  • Humans
  • Ketosis/complications
  • Long QT Syndrome/complications
  • Oxidative Stress
  • Vagus Nerve/physiopathology
  • Vitamin D Deficiency/complications
  • Water-Electrolyte Imbalance/complications


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