Ictal haemodynamic changes in a patient affected by "subtle" Epilepsia Partialis Continua

Anna Elisabetta Vaudano, Carlo Di Bonaventura, Marco Carni, Roman Rodionov, Leonardo Lapenta, Sara Casciato, Jinane Fattouch, Gabriella Egeo, Patrizia Pantano, Valter Nucciarelli, Bruno Maraviglia, Massimiliano Prencipe, Louis Lemieux, Anna Teresa Giallonardo

Research output: Contribution to journalArticlepeer-review


We report on a 64 year-old woman presenting with Epilepsia Partialis Continua (EPC) affecting the left hand since the age of 24 without neurological deficit. Structural MRI showed a region of focal cortical dysplasia (FCD) over the right central gyrus and lesions in the mesial frontal and occipital cortex secondary to perinatal hypoxic injury. Ictal spike haemodynamic mapping using simultaneous EEG-fMRI revealed significant BOLD signal changes prominent in the region of FCD (larger cluster), occipital cortex (global statistical maximum), prefrontal cortex and cerebellum. The cluster over FCD was in good agreement with the result of EEG source analysis. Our findings provide an interesting illustration of the ability of EEG-fMRI to reveal epileptogenic networks confirming the intrinsic epileptogenic properties of dysplastic neurons.

Original languageEnglish
Pages (from-to)65-69
Number of pages5
Issue number1
Publication statusPublished - Jan 2012


  • EEG/fMRI
  • Epilepsia Partialis Continua
  • Focal cortical dysplasia

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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