TY - JOUR
T1 - Hyponatremia in infants with new onset moderate-severe bronchiolitis
T2 - A cross-sectional study
AU - Milani, Gregorio P.
AU - Rocchi, Alessia
AU - Teatini, Thomas
AU - Bianchetti, Mario G.
AU - Amelio, Giacomo
AU - Mirra, Nadia
AU - Grava, Angela
AU - Agostoni, Carlo
AU - Fossali, Emilio F.
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Background The reported cumulative prevalence of hyponatremia (sodium <135 mmol/L) in bronchiolitis is 28%. However, sodium level was never measured by direct potentiometry, the method recommended by the International Federation of Clinical Chemistry and Laboratory Medicine. Aim of this study was to assess the prevalence of hyponatremia, measured by direct potentiometry, in infants with moderate-severe bronchiolitis. Methods A prospective cross-sectional study was conducted in infants ≥1month and ≤24months of age with bronchiolitis. Results 160 consecutive infants were enrolled. Hyponatremia was observed in 91 (57%) patients and occurred more commonly in infants ≤6 months than in older infant (P < 0.005). Conclusion The first study on sodium level measured by the direct potentiometry in infants with bronchiolitis points out that the prevalence of hyponatremia is two-fold higher than so far reported.
AB - Background The reported cumulative prevalence of hyponatremia (sodium <135 mmol/L) in bronchiolitis is 28%. However, sodium level was never measured by direct potentiometry, the method recommended by the International Federation of Clinical Chemistry and Laboratory Medicine. Aim of this study was to assess the prevalence of hyponatremia, measured by direct potentiometry, in infants with moderate-severe bronchiolitis. Methods A prospective cross-sectional study was conducted in infants ≥1month and ≤24months of age with bronchiolitis. Results 160 consecutive infants were enrolled. Hyponatremia was observed in 91 (57%) patients and occurred more commonly in infants ≤6 months than in older infant (P < 0.005). Conclusion The first study on sodium level measured by the direct potentiometry in infants with bronchiolitis points out that the prevalence of hyponatremia is two-fold higher than so far reported.
KW - Children
KW - Direct potentiometry
KW - Dysnatremia
KW - Electrolytes
KW - Indirect potentiometry
KW - Lower respiratory tract infection
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U2 - 10.1016/j.rmed.2017.10.028
DO - 10.1016/j.rmed.2017.10.028
M3 - Article
AN - SCOPUS:85034807613
SN - 0954-6111
VL - 133
SP - 48
EP - 50
JO - Respiratory Medicine
JF - Respiratory Medicine
ER -