Hyperparathyroidism during growth hormone treatment: A role for puberty?

Stefano Picca, Marco Cappa, Gianfranco Rizzoni

Research output: Contribution to journalArticlepeer-review


We describe three adolescent patients on chronic hemodialysis with a pubertal growth spurt who developed severe hyperparathyroidism during recombinant human growth hormone treatment. Parathyroid hormone levels were raised in parallel with the increase in linear growth in all patients. In two patients, hyperparathyroidism was successfully controlled with an increase in calcitriol dosage. In the third patient, growth hormone had to be withdrawn. We discuss the possibility that puberty is a risk factor for the development of hyperparathyroidism during growth hormone therapy.

Original languageEnglish
Pages (from-to)56-58
Number of pages3
JournalPediatric Nephrology
Issue number1
Publication statusPublished - 2000


  • Growth hormone
  • Hemodialysis
  • Hyperparathyroidism
  • Puberty

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health


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