Hyperkeratotic dermatitis

Marina Agozzino, Elvira Moscarella, Silvana Trincone, Marco Ardigò

Research output: Chapter in Book/Report/Conference proceedingChapter


The definition of hyperkeratotic skin diseases is referred to inflammatory skin disorders, clinically characterized by scaling and erythema, and microscopically showing variable thickening of the stratum corneum and epidermis (acanthosis) associated with variable degree of inflammation involving epidermis and dermis. Hyperkeratosis can be orthokeratotic as well as with parakeratosis; acanthosis can be regular, generally associated with papillomatosis (i.e. in psoriasis) or irregularly distributed and with different degree of epidermal thickening. Papillomatosis, histopathologically, is seen as elongation of the rete ridges, dilated dermal papillae and normal epidermal structures. The main hyperkeratotic skin diseases, in terms of frequency and social impact, are plaque psoriasis and seborrheic dermatitis.

Original languageEnglish
Title of host publicationReflectance Confocal Microscopy for Skin Diseases
PublisherSpringer Berlin Heidelberg
Number of pages13
ISBN (Print)9783642219979, 9783642219962
Publication statusPublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)


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