Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy

G. Zehender; L. Meroni; S. Varchetta; C. De Maddalena; B. Cavalli; M. Gianotto; A. B. Bosisio; C. Colasante; G. Rizzardini; M. Moroni; M. Galli

Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy

G. Zehender, L. Meroni, S. Varchetta, C. De Maddalena, B. Cavalli, M. Gianotto, A. B. Bosisio, C. Colasante, G. Rizzardini, M. Moroni, M. Galli

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

We investigated the presence of human T-lymphotropic virus type 2 (HTLV- 2) DNA in the peripheral blood mononuclear cell subsets obtained from 18 patients coinfected with human immunodeficiency virus type 1 and HTLV-2, 6 of whom also had predominantly sensory polyneuropathy (PSP). HTLV-2 DNA and RNA were found in CD8- and CD19-positive cells, and, for patients with PSP, in CD14-positive cells as well. Furthermore, the patients with PSP had higher proviral loads than those without PSP.

Original language	English
Pages (from-to)	7664-7668
Number of pages	5
Journal	Journal of Virology
Volume	72
Issue number	9
Publication status	Published - 1998

ASJC Scopus subject areas

Immunology

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Zehender, G., Meroni, L., Varchetta, S., De Maddalena, C., Cavalli, B., Gianotto, M., Bosisio, A. B., Colasante, C., Rizzardini, G., Moroni, M., & Galli, M. (1998). Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy. Journal of Virology, 72(9), 7664-7668.

Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy. / Zehender, G.; Meroni, L.; Varchetta, S. et al.

In: Journal of Virology, Vol. 72, No. 9, 1998, p. 7664-7668.

Research output: Contribution to journal › Article › peer-review

Zehender, G, Meroni, L, Varchetta, S, De Maddalena, C, Cavalli, B, Gianotto, M, Bosisio, AB, Colasante, C, Rizzardini, G, Moroni, M & Galli, M 1998, 'Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy', Journal of Virology, vol. 72, no. 9, pp. 7664-7668.

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abstract = "We investigated the presence of human T-lymphotropic virus type 2 (HTLV- 2) DNA in the peripheral blood mononuclear cell subsets obtained from 18 patients coinfected with human immunodeficiency virus type 1 and HTLV-2, 6 of whom also had predominantly sensory polyneuropathy (PSP). HTLV-2 DNA and RNA were found in CD8- and CD19-positive cells, and, for patients with PSP, in CD14-positive cells as well. Furthermore, the patients with PSP had higher proviral loads than those without PSP.",

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AU - Meroni, L.

AU - Varchetta, S.

AU - De Maddalena, C.

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AU - Gianotto, M.

AU - Bosisio, A. B.

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AU - Rizzardini, G.

AU - Moroni, M.

AU - Galli, M.

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Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy

Abstract

ASJC Scopus subject areas

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