TY - JOUR
T1 - HPV and Chlamydia trachomatis co-detection in young asymptomatic women from high incidence area for cervical cancer
AU - Bellaminutti, Serena
AU - Seraceni, Silva
AU - de Seta, Francesco
AU - Gheit, Tarik
AU - Tommasino, Massimo
AU - Comar, Manola
PY - 2014
Y1 - 2014
N2 - Chlamydia trachomatis causing chronic inflammatory diseases has investigated as possible human papillomavirus (HPV) cofactor in cervical cancer. The aim of this study is to evaluate the prevalence of Chlamydia trachomatis and HPV co-infection in different cohorts of asymptomatic women from a Northern Italy area at high incidence for cervical cancer. Cervical samples from 441 females were collected from Cervical Cancer Screening Program, Sexually Transmitted Infectious and Assisted Reproductive Technology centres. HPV and Chlamydia trachomatis were detected simultaneously and genotyped using a highly sensitive bead based assay. The overall prevalence of Chlamydia trachomatis was estimated 9.7%, in contrast with the reported national data of 2.3%, and co-infection with HPV was diagnosed in the 17% of the samples. In females ≤25 years of age, the infection reached a peak of 22% and co-infection with HPV of 45.8% (P
AB - Chlamydia trachomatis causing chronic inflammatory diseases has investigated as possible human papillomavirus (HPV) cofactor in cervical cancer. The aim of this study is to evaluate the prevalence of Chlamydia trachomatis and HPV co-infection in different cohorts of asymptomatic women from a Northern Italy area at high incidence for cervical cancer. Cervical samples from 441 females were collected from Cervical Cancer Screening Program, Sexually Transmitted Infectious and Assisted Reproductive Technology centres. HPV and Chlamydia trachomatis were detected simultaneously and genotyped using a highly sensitive bead based assay. The overall prevalence of Chlamydia trachomatis was estimated 9.7%, in contrast with the reported national data of 2.3%, and co-infection with HPV was diagnosed in the 17% of the samples. In females ≤25 years of age, the infection reached a peak of 22% and co-infection with HPV of 45.8% (P
KW - Cancer co-factors
KW - Cervical lesions
KW - Chlamydia trachomatis
KW - Chlamydia trachomatis screening
KW - Human papillomavirus
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U2 - 10.1002/jmv.24041
DO - 10.1002/jmv.24041
M3 - Article
C2 - 25132162
AN - SCOPUS:84944224992
SN - 0146-6615
VL - 86
SP - 1920
EP - 1925
JO - Journal of Medical Virology
JF - Journal of Medical Virology
IS - 11
ER -