HLA-A3 linked C3 deficiency in multiple sclerosis

D. Caputo, G. Bisaccia, M. G. Sabbadini, A. Zibetti

Research output: Contribution to journalArticlepeer-review


Many researchers claim variations in quantity of functional activity of several components in the complement system in M.S. patients. Studies were performed in 58 M.S. patients, typing for HLA-SD specificities and C'3 complement component. The authors have been able to confirm a significant correlation between the hypocomplementaemic group (31.03%) with HLA-A3. In this connection the authors present some considerations on complement system and M.S.

Original languageEnglish
Pages (from-to)260-263
Number of pages4
JournalBollettino dell'Istituto Sieroterapico Milanese
Issue number3
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Immunology


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