TY - JOUR
T1 - Histology far away from Flatland
T2 - 3D roller-coasting into grade-dependent angiogenetic patterns in oligodendrogliomas: Images in Cellular/Molecular Medicine
AU - Cassoni, P.
AU - Gaetano, L.
AU - Senetta, R.
AU - Bussolati, B.
AU - Molinaro, L.
AU - Bussolati, G.
PY - 2008/4
Y1 - 2008/4
N2 - Angiogenesis plays a key role in tumour progression, and undergoes structural changes associated to tumour biology itself. Although vessel density can be easily evaluated in brain tumours using a traditional immuno-histochemical approach, other parameters of conceptual/biological interest, such as the complex patterns of vascular growth, cannot be fully understood using a traditional bi-dimensional evaluation. We use here surgical specimens derived from oligodendrogliomas as a model for a novel elucidative 3D reconstruction of the grade-dependent vascular arborisation in brain tumours.
AB - Angiogenesis plays a key role in tumour progression, and undergoes structural changes associated to tumour biology itself. Although vessel density can be easily evaluated in brain tumours using a traditional immuno-histochemical approach, other parameters of conceptual/biological interest, such as the complex patterns of vascular growth, cannot be fully understood using a traditional bi-dimensional evaluation. We use here surgical specimens derived from oligodendrogliomas as a model for a novel elucidative 3D reconstruction of the grade-dependent vascular arborisation in brain tumours.
KW - 3D
KW - Angiogenesis
KW - Oligodendroglioma
UR - http://www.scopus.com/inward/record.url?scp=42349094303&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=42349094303&partnerID=8YFLogxK
U2 - 10.1111/j.1582-4934.2007.00206.x
DO - 10.1111/j.1582-4934.2007.00206.x
M3 - Article
C2 - 18182068
AN - SCOPUS:42349094303
SN - 1582-1838
VL - 12
SP - 564
EP - 568
JO - Journal of Cellular and Molecular Medicine
JF - Journal of Cellular and Molecular Medicine
IS - 2
ER -