High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy

A. M. Carella; G. Santini; D. Giordano; F. Frassoni; S. Nati; A. Congiu; D. Occhini; E. Rossi; M. Martinengo; E. Damasio

doi:10.1002/1097-0142(19841215)54:12<2836::AID-CNCR2820541203>3.0.CO;2-R

High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy

A. M. Carella, G. Santini, D. Giordano, F. Frassoni, S. Nati, A. Congiu, D. Occhini, E. Rossi, M. Martinengo, E. Damasio

Research output: Contribution to journal › Article › peer-review

Abstract

Ten patients with advanced, diffuse Hodgkin's and non-Hodgkin's lymphomas responding poorly to the most widely employed primary chemotherapy regimens were treated with a high-dose chemotherapy (HDC) followed by rescue with non-frozen autologous bone marrow infusion (ABMT). Complete remission (CR) was obtained in seven of ten patients (70%) and partial remission in two. Hemopoietic recovery occurred in nine cases. These preliminary results appear to indicate that HDC and non-frozen ABMT may be successfully used in patients with resistant or relapsed lymphomas.

Original language	English
Pages (from-to)	2836-2839
Number of pages	4
Journal	Cancer
Volume	54
Issue number	12
DOIs	https://doi.org/10.1002/1097-0142(19841215)54:12<2836::AID-CNCR2820541203>3.0.CO;2-R
Publication status	Published - 1984

ASJC Scopus subject areas

Cancer Research
Oncology

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10.1002/1097-0142(19841215)54:12<2836::AID-CNCR2820541203>3.0.CO;2-R

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Carella, A. M., Santini, G., Giordano, D., Frassoni, F., Nati, S., Congiu, A., Occhini, D., Rossi, E., Martinengo, M., & Damasio, E. (1984). High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy. Cancer, 54(12), 2836-2839. https://doi.org/10.1002/1097-0142(19841215)54:12<2836::AID-CNCR2820541203>3.0.CO;2-R

Carella, AM, Santini, G, Giordano, D, Frassoni, F, Nati, S, Congiu, A, Occhini, D, Rossi, E, Martinengo, M & Damasio, E 1984, 'High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy', Cancer, vol. 54, no. 12, pp. 2836-2839. https://doi.org/10.1002/1097-0142(19841215)54:12<2836::AID-CNCR2820541203>3.0.CO;2-R

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AU - Carella, A. M.

AU - Santini, G.

AU - Giordano, D.

AU - Frassoni, F.

AU - Nati, S.

AU - Congiu, A.

AU - Occhini, D.

AU - Rossi, E.

AU - Martinengo, M.

AU - Damasio, E.

PY - 1984

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AB - Ten patients with advanced, diffuse Hodgkin's and non-Hodgkin's lymphomas responding poorly to the most widely employed primary chemotherapy regimens were treated with a high-dose chemotherapy (HDC) followed by rescue with non-frozen autologous bone marrow infusion (ABMT). Complete remission (CR) was obtained in seven of ten patients (70%) and partial remission in two. Hemopoietic recovery occurred in nine cases. These preliminary results appear to indicate that HDC and non-frozen ABMT may be successfully used in patients with resistant or relapsed lymphomas.

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High-dose chemotherapy and non-frozen autologous bone marrow transplantation in relapsed advanced lymphomas or those resistant to conventional chemotherapy

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