TY - JOUR
T1 - High diagnostic accuracy of prospective ECG-gating 64-slice computed tomography coronary angiography for the detection of in-stent restenosis
T2 - In-stent restenosis assessment by low-dose MDCT
AU - Andreini, Daniele
AU - Pontone, Gianluca
AU - Bartorelli, Antonio L.
AU - Mushtaq, Saima
AU - Trabattoni, Daniela
AU - Bertella, Erika
AU - Cortinovis, Sarah
AU - Annoni, Andrea
AU - Formenti, Alberto
AU - Ballerini, Giovanni
AU - Agostoni, Piergiuseppe
AU - Fiorentini, Cesare
AU - Pepi, Mauro
PY - 2011/7
Y1 - 2011/7
N2 - Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈
AB - Objectives: The accuracy of computed tomography (CT) for assessment of coronary stents is as yet unproven and radiation exposure has been a concern. The aim of our study is to compare radiation dose and diagnostic performance of CT with prospective ECG-triggering versus retrospective ECG-triggering for the detection of in-stent restenosis (ISR). Methods: We enrolled 168 consecutive patients with suspected ISR, 83 studied using CT with prospective ECG-triggering (group 1) and 85 using retrospective ECG-triggering (group 2). Results: Prevalence of ISR according to catheter angiography was 24% in both groups. The overall evaluability was similar (93% in group 1 vs 95% in group 2). Artefact sub-analysis showed a significantly lower number of blooming and higher number of slice misalignment in group 1 vs group 2. In the stent-based analysis using only evaluable stents, specificity, positive predictive value and accuracy were significantly higher in group 1 (100%, 100% and 99%, respectively) than in group 2 (97%, 91% and 95%, respectively, p∈
KW - Computed tomography
KW - Coronary arteries
KW - Coronary stents
KW - In-stent restenosis
KW - Invasive coronary angiography
KW - Radiation dose
UR - http://www.scopus.com/inward/record.url?scp=79959376894&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79959376894&partnerID=8YFLogxK
U2 - 10.1007/s00330-011-2085-7
DO - 10.1007/s00330-011-2085-7
M3 - Article
C2 - 21331594
AN - SCOPUS:79959376894
SN - 0938-7994
VL - 21
SP - 1430
EP - 1438
JO - European Radiology
JF - European Radiology
IS - 7
ER -