Hepatitis B or C Virus Serology as a Prognostic Factor in Patients with Hepatocellular Carcinoma

Syed A. Ahmad, Malcolm M. Bilimoria, Xuemei Wang, Francesco Izzo, Paolo Delrio, Paolo Marra, Treneth P. Baker, Geoff A. Porter, Lee M. Ellis, Jean N. Vauthey, Sundar Dhamotharan, Steven A. Curley

Research output: Contribution to journalArticlepeer-review


It is not clear whether chronic hepatitis B or C virus (HBV or HCV) infection is a prognostic factor for hepatocellular carcinoma. We performed this study to determine if chronic HBV or HCV infection had any impact on postresection survival or affected patterns of failure. The records of 77 patients undergoing surgical resection for hepatocellular carcinoma between January 1990 and December 1998 were reviewed. Forty-four patients (57%) had HCV infection, 18 patients (23%) had HBV infection, and 15 patients (20%) had negative serology. There were no differences in age, sex, or tumor size among the groups, and all patients had margin-negative resections. There was a significantly higher incidence of satellitosis and vascular invasion in patients with HCV infection (32% and 41 %, respectively; P

Original languageEnglish
Pages (from-to)468-476
Number of pages9
JournalJournal of Gastrointestinal Surgery
Issue number5
Publication statusPublished - Sept 2001


  • Hepatitis B
  • Hepatitis C
  • Hepatocellular carcinoma
  • Prognostic factors

ASJC Scopus subject areas

  • Surgery


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