TY - JOUR
T1 - Helicobacter pylori stool antigen test
T2 - A method to confirm eradication in children
AU - Roggero, Paola
AU - Bonfiglio, Arianna
AU - Luzzani, Sergio
AU - Valadè, Alberto
AU - Cataliotti, Elena
AU - Corno, Giovanna
AU - Garlaschi, Maria Cristina
AU - Carissimi, Emanuela
AU - Mosca, Fabio
AU - Cornelli, Vittorio
PY - 2002
Y1 - 2002
N2 - We evaluated an antigen-based stool assay as an indicator of Helicobacter pylori (Hp) status during treatment aimed at eradicating Hp in 22 Hp-positive patients and 63 negative control patients. The sensitivity and specificity of the assay was 100% and 70%, respectively, when the manufacturer's cutoff was used. When we used the cutoff calculated from a receiver operating characteristic curve, the specificity of this test increased. Under these conditions, the test could be used in monitoring treatment and verifying eradication of Hp infection. Further studies must be carried out to standardize the cutoff in children.
AB - We evaluated an antigen-based stool assay as an indicator of Helicobacter pylori (Hp) status during treatment aimed at eradicating Hp in 22 Hp-positive patients and 63 negative control patients. The sensitivity and specificity of the assay was 100% and 70%, respectively, when the manufacturer's cutoff was used. When we used the cutoff calculated from a receiver operating characteristic curve, the specificity of this test increased. Under these conditions, the test could be used in monitoring treatment and verifying eradication of Hp infection. Further studies must be carried out to standardize the cutoff in children.
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U2 - 10.1067/mpd.2002.123662
DO - 10.1067/mpd.2002.123662
M3 - Article
C2 - 12072886
AN - SCOPUS:0036082561
SN - 0022-3476
VL - 140
SP - 775
EP - 777
JO - Journal of Pediatrics
JF - Journal of Pediatrics
IS - 6
ER -