Heart rate and cardiac allograft vasculopathy in heart transplant recipients

Francesca Olmetti, Gian Domenico Pinna, Roberto Maestri, Andrea D'Armini, Carlo Pellegrini, Mario Viganò, Daniele Lilleri, Giuseppe Gerna, Oreste Febo, Maria Teresa La Rovere

Research output: Contribution to journalArticlepeer-review


Background: Elevated heart rate (HR) has been indicated as risk factor for cardiovascular disease. Experimental data support a role of HR in the progression and severity of atherosclerotic lesions. Sinus tachycardia is common in heart transplant patients due to the lack of autonomic control. This study assessed the role of HR in the development of cardiac allograft vasculopathy (CAV) in heart transplant recipients. Methods: Data from 244 allograft recipients were analyzed. Known factors affecting CAV and mean HR obtained from 24-hour recordings at 1 year (dichotomized at

Original languageEnglish
Pages (from-to)1368-1373
Number of pages6
JournalJournal of Heart and Lung Transplantation
Issue number12
Publication statusPublished - Dec 2011


  • coronary allograft vasculopathy
  • donor age
  • heart rate

ASJC Scopus subject areas

  • Transplantation
  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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