Frailty and cardiac rehabilitation: A call to action from the EAPC Cardiac Rehabilitation Section

Carlo Vigorito, Ana Abreu, Marco Ambrosetti, Romualdo Belardinelli, Ugo Corrà, Margaret Cupples, Constantinos H. Davos, Stefan Hoefer, Marie Christine Iliou, Jean Paul Schmid, Heinz Voeller, Patrick Doherty

Research output: Contribution to journalArticlepeer-review


Frailty is a geriatric syndrome characterised by a vulnerability status associated with declining function of multiple physiological systems and loss of physiological reserves. Two main models of frailty have been advanced: the phenotypic model (primary frailty) or deficits accumulation model (secondary frailty), and different instruments have been proposed and validated to measure frailty. However measured, frailty correlates to medical outcomes in the elderly, and has been shown to have prognostic value for patients in different clinical settings, such as in patients with coronary artery disease, after cardiac surgery or transvalvular aortic valve replacement, in patients with chronic heart failure or after left ventricular assist device implantation. The prevalence, clinical and prognostic relevance of frailty in a cardiac rehabilitation setting has not yet been well characterised, despite the increasing frequency of elderly patients in cardiac rehabilitation, where frailty is likely to influence the onset, type and intensity of the exercise training programme and the design of tailored rehabilitative interventions for these patients. Therefore, we need to start looking for frailty in elderly patients entering cardiac rehabilitation programmes and become more familiar with some of the tools to recognise and evaluate the severity of this condition. Furthermore, we need to better understand whether exercise-based cardiac rehabilitation may change the course and the prognosis of frailty in cardiovascular patients.

Original languageEnglish
Pages (from-to)577-590
Number of pages14
JournalEuropean Journal of Preventive Cardiology
Issue number6
Publication statusPublished - Apr 2017


  • Cardiac rehabilitation
  • Elderly
  • Frailty

ASJC Scopus subject areas

  • Epidemiology
  • Cardiology and Cardiovascular Medicine


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