TY - CHAP
T1 - fMRI in neurodegenerative diseases
T2 - From scientific insights to clinical applications
AU - Dickerson, Bradford C.
AU - Agosta, Federica
AU - Filippi, Massimo
PY - 2016/9/1
Y1 - 2016/9/1
N2 - fMRI is a technology with great promise as a tool to probe abnormalities of brain activity in neurodegenerative diseases. The detection of functional brain abnormalities may be useful, in the appropriate clinical context, for early diagnosis, differential diagnosis, or prognostication. Prediction of response to treatment or therapeutic monitoring may also be possible with fMRI. In addition, fMRI has the potential to provide a variety of scientific insights that may have clinical relevance, including compensatory hyperactivation of brain circuits or genetic modulation of functional brain activity.
AB - fMRI is a technology with great promise as a tool to probe abnormalities of brain activity in neurodegenerative diseases. The detection of functional brain abnormalities may be useful, in the appropriate clinical context, for early diagnosis, differential diagnosis, or prognostication. Prediction of response to treatment or therapeutic monitoring may also be possible with fMRI. In addition, fMRI has the potential to provide a variety of scientific insights that may have clinical relevance, including compensatory hyperactivation of brain circuits or genetic modulation of functional brain activity.
KW - Alzheimer’s disease
KW - Amyotrophic lateral sclerosis
KW - Functional MRI
KW - Huntington disease
KW - Magnetic resonance imaging
KW - Neurodegenerative diseases
KW - Parkinson’s disease
UR - http://www.scopus.com/inward/record.url?scp=84988890260&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84988890260&partnerID=8YFLogxK
U2 - 10.1007/978-1-4939-5611-1_23
DO - 10.1007/978-1-4939-5611-1_23
M3 - Chapter
AN - SCOPUS:84988890260
VL - 119
T3 - Neuromethods
SP - 699
EP - 739
BT - Neuromethods
PB - Humana Press Inc.
ER -