First impressions about Adherus, a new dural sealant

Cesare Zoia; Daniele Bongetta; Francesco Lombardi; Viola Marta Custodi; Raffaelino Pugliese; Paolo Gaetani

doi:10.5301/jabfm.5000241

First impressions about Adherus, a new dural sealant

Cesare Zoia, Daniele Bongetta, Francesco Lombardi, Viola Marta Custodi, Raffaelino Pugliese, Paolo Gaetani

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.

Original language	English
Pages (from-to)	e372-e375
Journal	Journal of Applied Biomaterials and Functional Materials
Volume	13
Issue number	4
DOIs	https://doi.org/10.5301/jabfm.5000241
Publication status	Published - 2015

Keywords

Dural sealant
Polytheyleneimine
Postoperative cerebrospinal fluid leaks
Transphenoidal endoscopic surgery

ASJC Scopus subject areas

Biophysics
Bioengineering
Biomedical Engineering
Biomaterials

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10.5301/jabfm.5000241

Cite this

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abstract = "Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.",

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T1 - First impressions about Adherus, a new dural sealant

AU - Zoia, Cesare

AU - Bongetta, Daniele

AU - Lombardi, Francesco

AU - Custodi, Viola Marta

AU - Pugliese, Raffaelino

AU - Gaetani, Paolo

PY - 2015

Y1 - 2015

N2 - Purpose: The aim of the study is to report our first impressions about Adherus, a novel dural sealant, used in neurosurgical endoscopic transnasal procedures. Methods: We retrospectively reviewed the clinical and surgical records of the first 11 patients with intraoperative high-flow cerebrospinal fluid leak treated with the aid of Adherus at our center between February and October 2014. The healing at the level of the dural plasty was monitored and evaluated radiologically and with regular endoscopic inspections. Results: With a median follow-up of 210 days, no postoperative CSF leak or surgical site infections were found in any of the cases. Conclusions: Based on our preliminary experience, this new dural sealant seems to provide an effective aid in dural plasty during endoscopic transphenoidal procedures.

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KW - Dural sealant

KW - Polytheyleneimine

KW - Postoperative cerebrospinal fluid leaks

KW - Transphenoidal endoscopic surgery

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First impressions about Adherus, a new dural sealant

Abstract

Keywords

ASJC Scopus subject areas

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