Filberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary infiltrates after BMT in children

E. Lanino, O. Sacco, Z. Kotitsa, A. Rabagliati, E. Castagnola, A. Garaventa, S. Dallorso, A. Gandolfo, L. Manfredini, P. Venzano, C. Savioli, L. Macciò, G. Dini, G. A. Rossi

Research output: Contribution to journalArticlepeer-review

Abstract

Thirty-one fiberoptic bronchoscopies and BAL performed within 4 days after the appareance of pulmonary infiltrates in 28 children who received BMT were reviewed. A causative agent was identified in 67% of patients with diffuse infiltrates (Cytomegalovirus in 8 cases, Pneumocystis carinii in 4) and in 31% of those with localized infiltrates (Aspergillus in 2, bacteria in 2). No relevant side effect was reported. The results obtained from cytological and microbiological testing provided relevant informations for the management of most cases, regardless to the identification of a specific pathogen. We conclude that PAL is a safe diagnostic procedure that should be considered early after the onset of pulmonary complications in BMT recipients.

Original languageEnglish
Pages (from-to)117-120
Number of pages4
JournalBone Marrow Transplantation
Volume18
Issue numberSUPPL. 2
Publication statusPublished - Nov 1996

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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