Fibrous hamartoma of infancy: An Italian multi-institutional experience

Elena Carretto, Patrizia Dall'Igna, Rita Alaggio, Fortunato Siracusa, Claudio Granata, Andrea Ferrari, Giovanni Cecchetto

Research output: Contribution to journalArticlepeer-review


Background: Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. Objective and Methods: The clinical features and treatment results of 18 children with FH are described. Results: Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery. Limitations: The results did not reach statistical significance due to difficulties in collecting cases. Conclusions: FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.

Original languageEnglish
Pages (from-to)800-803
Number of pages4
JournalJournal of the American Academy of Dermatology
Issue number5
Publication statusPublished - May 2006

ASJC Scopus subject areas

  • Dermatology


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