Faster Initial Viral Decay in Female Children Living With HIV

Sara Domínguez-Rodríguez; Miquel Serna-Pascual; Caroline Foster; Paolo Palma; Eleni Nastouli; Anita De Rossi; Javier Seoane; Paolo Rossi; Carlo Giaquinto; Alfredo Tagarro; Pablo Rojo

doi:10.1093/jpids/piaa174

Faster Initial Viral Decay in Female Children Living With HIV

Sara Domínguez-Rodríguez, Miquel Serna-Pascual, Caroline Foster, Paolo Palma, Eleni Nastouli, Anita De Rossi, Javier Seoane, Paolo Rossi, Carlo Giaquinto, Alfredo Tagarro, Pablo Rojo

Research output: Contribution to journal › Article › peer-review

Abstract

Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males.

Original language	English
Pages (from-to)	674-676
Number of pages	3
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	10
Issue number	5
DOIs	https://doi.org/10.1093/jpids/piaa174
Publication status	Published - May 28 2021

Keywords

Anti-HIV Agents/therapeutic use
Child
Female
HIV Infections/drug therapy
HIV-1
Humans
Male
Viral Load

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10.1093/jpids/piaa174

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title = "Faster Initial Viral Decay in Female Children Living With HIV",

abstract = "Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males.",

keywords = "Anti-HIV Agents/therapeutic use, Child, Female, HIV Infections/drug therapy, HIV-1, Humans, Male, Viral Load",

author = "Sara Dom{\'i}nguez-Rodr{\'i}guez and Miquel Serna-Pascual and Caroline Foster and Paolo Palma and Eleni Nastouli and {De Rossi}, Anita and Javier Seoane and Paolo Rossi and Carlo Giaquinto and Alfredo Tagarro and Pablo Rojo",

note = "{\textcopyright} The Author(s) 2021. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.",

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doi = "10.1093/jpids/piaa174",

language = "English",

volume = "10",

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journal = "Journal of the Pediatric Infectious Diseases Society",

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TY - JOUR

T1 - Faster Initial Viral Decay in Female Children Living With HIV

AU - Domínguez-Rodríguez, Sara

AU - Serna-Pascual, Miquel

AU - Foster, Caroline

AU - Palma, Paolo

AU - Nastouli, Eleni

AU - De Rossi, Anita

AU - Seoane, Javier

AU - Rossi, Paolo

AU - Giaquinto, Carlo

AU - Tagarro, Alfredo

AU - Rojo, Pablo

N1 - © The Author(s) 2021. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

PY - 2021/5/28

Y1 - 2021/5/28

N2 - Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males.

AB - Limited data exist regarding sex bias and viral decay in children with HIV. We investigated the sex differences in viral decay in 25 perinatally HIV-infected children. Females presented faster phase I viral decay regardless of their age at antiretroviral therapy (ART) initiation, baseline CD4 percentages, or baseline RNA levels. Also, for each month elapsed under ART, females had faster viral decay than males.

KW - Anti-HIV Agents/therapeutic use

KW - Child

KW - Female

KW - HIV Infections/drug therapy

KW - HIV-1

KW - Humans

KW - Male

KW - Viral Load

U2 - 10.1093/jpids/piaa174

DO - 10.1093/jpids/piaa174

M3 - Article

C2 - 33491084

SN - 2048-7193

VL - 10

SP - 674

EP - 676

JO - Journal of the Pediatric Infectious Diseases Society

JF - Journal of the Pediatric Infectious Diseases Society

IS - 5

ER -

Faster Initial Viral Decay in Female Children Living With HIV

Abstract

Keywords

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