Experiences with immunomodulant agents in HIV infections

A. Lazzarin; W. Barcellini; C. Uberti Foppa; M. O. Borghi; F. Franzetti; P. Cinque; M. Moroni

doi:10.1159/000205909

Experiences with immunomodulant agents in HIV infections

A. Lazzarin, W. Barcellini, C. Uberti Foppa, M. O. Borghi, F. Franzetti, P. Cinque, M. Moroni

Research output: Contribution to journal › Article › peer-review

Abstract

Drug addicts with persistent generalized lymphadenopathy displayed the following immunological abnormalities: An inverted OKT4/OKT8 ratio, a depressed in vitro blastogenetic response to phytohemagglutinin and pokeweed mitogen (PWM), a reduced ability of PMNL to phagocytose and kill Candida albicans spores and to migrate in presence of a chemotactic factor. Thymopentin treatment (50 mg s.c. 3 times/week for 3 weeks and repeated after 3 months at 50 mg s.c. once a week for 3 months) improved OKT4+ lymphocytes (p

Original language	English
Pages (from-to)	84-90
Number of pages	7
Journal	Acta Haematologica
Volume	78
DOIs	https://doi.org/10.1159/000205909
Publication status	Published - 1987

Keywords

Candida albicans test
HIV infection
Thymopentin

ASJC Scopus subject areas

Hematology

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10.1159/000205909

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AU - Borghi, M. O.

AU - Franzetti, F.

AU - Cinque, P.

AU - Moroni, M.

PY - 1987

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N2 - Drug addicts with persistent generalized lymphadenopathy displayed the following immunological abnormalities: An inverted OKT4/OKT8 ratio, a depressed in vitro blastogenetic response to phytohemagglutinin and pokeweed mitogen (PWM), a reduced ability of PMNL to phagocytose and kill Candida albicans spores and to migrate in presence of a chemotactic factor. Thymopentin treatment (50 mg s.c. 3 times/week for 3 weeks and repeated after 3 months at 50 mg s.c. once a week for 3 months) improved OKT4+ lymphocytes (p

AB - Drug addicts with persistent generalized lymphadenopathy displayed the following immunological abnormalities: An inverted OKT4/OKT8 ratio, a depressed in vitro blastogenetic response to phytohemagglutinin and pokeweed mitogen (PWM), a reduced ability of PMNL to phagocytose and kill Candida albicans spores and to migrate in presence of a chemotactic factor. Thymopentin treatment (50 mg s.c. 3 times/week for 3 weeks and repeated after 3 months at 50 mg s.c. once a week for 3 months) improved OKT4+ lymphocytes (p

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Experiences with immunomodulant agents in HIV infections

Abstract

Keywords

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