Epithelioid osteosarcoma of the jaw

Raffaele Cozza, Rita Devito, Maria Antonietta De Ioris, Mario Zama, Renata Boldrini, Paola Fidani, Alberto Donfrancesco

Research output: Contribution to journalArticlepeer-review


Epithelioid osteosarcoma (OS) is a rare sub-type of OS with an aggressive behavior. An epithelioid OS was diagnosed in an 8-yearold female with painful swelling of the left jaw. After two courses of chemotherapy (cisplatin/ methotrexate/doxorubicin), the patient presented a progressive disease. After hemimandibulectomy, 13 courses of post-operative chemotherapy (cisplatin/methotrexate/doxorubicin/ifosfamide) were performed. Histological and ultra-structural examination showed a high grade neoplasm consisting of sheets of epithelioid cells with focal osteoid formation. The patient is alive and in complete remission 42 months from diagnosis.

Original languageEnglish
Pages (from-to)877-879
Number of pages3
JournalPediatric Blood and Cancer
Issue number7
Publication statusPublished - Jul 1 2009


  • Epithelioid sub-type
  • Jaw
  • Osteosarcoma

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology


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