One hundred and forty-three patients affected by primary supratentorial brain tumours were studied in order to describe the incidence of epileptic seizures at presentation and in the course of the illness 45 patients affected by glioblastoma, 30 by anaplastic astrocytoma, 30 by astrocytoma low grade and 38 by meningioma were studied. Anticonvulsant efficacy and toxic side effects were evaluated in two groups of patients treated with Phenobarbital or Vigabatrin. Our study shows an inverse relationship between tumour grade and seizures frequency in glial tumours. The course of seizures subsequent to the diagnosis of the neoplasm was significantly related to the presence or absence of seizures at presentation. The use of prophylactic anticonvulsants in the treatment of these patients should be studied in more large series.
|Translated title of the contribution||Epilepsy at presentation and in the course of the illness in 143 affected by supratentorial brain tumors|
|Number of pages||2|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - 1997|
ASJC Scopus subject areas
- Clinical Neurology