Epidemiology of acute promyelocytic leukemia in Italy

G. Avvisati; A. Mele; M. A. Stazi; M. L. Vegna; P. Pasquini; F. Mandelli; B. Rotoli; G. De Rosa; G. Papa; A. Venditti; P. Citarrella; M. Tambone Reyes; E. Ascari; R. Invernizzi; A. Cajozzo; M. Musso; A. Alberti; A. Peta; P. Rossi Ferrini

Epidemiology of acute promyelocytic leukemia in Italy

G. Avvisati, A. Mele, M. A. Stazi, M. L. Vegna, P. Pasquini, F. Mandelli, B. Rotoli, G. De Rosa, G. Papa, A. Venditti, P. Citarrella, M. Tambone Reyes, E. Ascari, R. Invernizzi, A. Cajozzo, M. Musso, A. Alberti, A. Peta, P. Rossi Ferrini

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

This retrospective epidemiologic study on 256 cases of acute promyelocytic leukemia (APL) observed in 20 Italian hematology centers between 1980 and 1988 demonstrated that APL is different from the other acute non-lymphocytic leukemias (ANLL). The male/female ratio was 0.9; median age at diagnosis was 40 years (with 80% of patients between 15 and 54 years of age). The minimal annual incidence of APL in Italy per 1,000,000 inhabitants was estimated to be 0.6; an increased incidence was observed in spring and in autumn. The overall median survival duration of APL patients was 12.6 months. From an epidemiological point of view APL is a distinctive subtype of ANLL.

Original language	English
Pages (from-to)	405-408
Number of pages	4
Journal	Annals of Oncology
Volume	2
Issue number	6
Publication status	Published - 1991

ASJC Scopus subject areas

Cancer Research
Oncology
Statistics, Probability and Uncertainty
Applied Mathematics
Public Health, Environmental and Occupational Health
Neuropsychology and Physiological Psychology
Hematology

Cite this

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title = "Epidemiology of acute promyelocytic leukemia in Italy",

abstract = "This retrospective epidemiologic study on 256 cases of acute promyelocytic leukemia (APL) observed in 20 Italian hematology centers between 1980 and 1988 demonstrated that APL is different from the other acute non-lymphocytic leukemias (ANLL). The male/female ratio was 0.9; median age at diagnosis was 40 years (with 80% of patients between 15 and 54 years of age). The minimal annual incidence of APL in Italy per 1,000,000 inhabitants was estimated to be 0.6; an increased incidence was observed in spring and in autumn. The overall median survival duration of APL patients was 12.6 months. From an epidemiological point of view APL is a distinctive subtype of ANLL.",

author = "G. Avvisati and A. Mele and Stazi, {M. A.} and Vegna, {M. L.} and P. Pasquini and F. Mandelli and B. Rotoli and {De Rosa}, G. and G. Papa and A. Venditti and P. Citarrella and {Tambone Reyes}, M. and E. Ascari and R. Invernizzi and A. Cajozzo and M. Musso and A. Alberti and A. Peta and {Rossi Ferrini}, P.",

year = "1991",

language = "English",

volume = "2",

pages = "405--408",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "NLM (Medline)",

number = "6",

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TY - JOUR

T1 - Epidemiology of acute promyelocytic leukemia in Italy

AU - Avvisati, G.

AU - Mele, A.

AU - Stazi, M. A.

AU - Vegna, M. L.

AU - Pasquini, P.

AU - Mandelli, F.

AU - Rotoli, B.

AU - De Rosa, G.

AU - Papa, G.

AU - Venditti, A.

AU - Citarrella, P.

AU - Tambone Reyes, M.

AU - Ascari, E.

AU - Invernizzi, R.

AU - Cajozzo, A.

AU - Musso, M.

AU - Alberti, A.

AU - Peta, A.

AU - Rossi Ferrini, P.

PY - 1991

Y1 - 1991

N2 - This retrospective epidemiologic study on 256 cases of acute promyelocytic leukemia (APL) observed in 20 Italian hematology centers between 1980 and 1988 demonstrated that APL is different from the other acute non-lymphocytic leukemias (ANLL). The male/female ratio was 0.9; median age at diagnosis was 40 years (with 80% of patients between 15 and 54 years of age). The minimal annual incidence of APL in Italy per 1,000,000 inhabitants was estimated to be 0.6; an increased incidence was observed in spring and in autumn. The overall median survival duration of APL patients was 12.6 months. From an epidemiological point of view APL is a distinctive subtype of ANLL.

AB - This retrospective epidemiologic study on 256 cases of acute promyelocytic leukemia (APL) observed in 20 Italian hematology centers between 1980 and 1988 demonstrated that APL is different from the other acute non-lymphocytic leukemias (ANLL). The male/female ratio was 0.9; median age at diagnosis was 40 years (with 80% of patients between 15 and 54 years of age). The minimal annual incidence of APL in Italy per 1,000,000 inhabitants was estimated to be 0.6; an increased incidence was observed in spring and in autumn. The overall median survival duration of APL patients was 12.6 months. From an epidemiological point of view APL is a distinctive subtype of ANLL.

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C2 - 1768626

AN - SCOPUS:0025797687

SN - 0923-7534

VL - 2

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EP - 408

JO - Annals of Oncology

JF - Annals of Oncology

IS - 6

ER -

Epidemiology of acute promyelocytic leukemia in Italy

Abstract

ASJC Scopus subject areas

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