Epidemiology and costs of herpes zoster: Background data to estimate the impact of vaccination

Valeria Di Legami; Maria Michela Gianino; Marta Ciofi Degli Atti; Marco Massari; Alessandro Migliardi; Gianpaolo Scalia Tomba; Carla Zotti

doi:10.1016/j.vaccine.2007.07.049

Epidemiology and costs of herpes zoster: Background data to estimate the impact of vaccination

Valeria Di Legami, Maria Michela Gianino, Marta Ciofi Degli Atti, Marco Massari, Alessandro Migliardi, Gianpaolo Scalia Tomba, Carla Zotti

Ospedale Pediatrico Bambino Gesu

Research output: Contribution to journal › Article › peer-review

Abstract

In 2004, we conducted a study in Piemonte (Italy), in order to describe incidence, treatment, hospitalizations and costs of herpes zoster (HZ), in population over 14 years of age. Twenty-four regional general practitioners, with 26,394 patients >14 years in charge (0.71% of the regional population), reported prospectively all diagnosed HZ cases. In addition, all regional hospital discharge records were reviewed. Forty-six HZ cases treated at home were reported, accounting for a total incidence of 1.74 cases/1000 population >14 years per year. HZ rate standardized by age on regional population 14 years older is 1.59/1000. The cost per observed home case was €136.06. The incidence of hospital admissions was 0.12/1000 inhabitants. The mean cost of hospitalized cases was €4082.59. These results contribute to depict the impact of HZ in the general population, and to provide background data for setting-up either mathematical models aimed to estimate the impact of vaccination on HZ, and the cost-benefit analyses of various preventive and therapeutic scenarios.

Original language	English
Pages (from-to)	7598-7604
Number of pages	7
Journal	Vaccine
Volume	25
Issue number	43
DOIs	https://doi.org/10.1016/j.vaccine.2007.07.049
Publication status	Published - Oct 23 2007

Keywords

Costs
General practitioners
Herpes zoster
Hospital admissions
Incidence
Treatments

ASJC Scopus subject areas

Immunology
Microbiology
Virology
Infectious Diseases
Public Health, Environmental and Occupational Health
veterinary(all)

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10.1016/j.vaccine.2007.07.049

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title = "Epidemiology and costs of herpes zoster: Background data to estimate the impact of vaccination",

abstract = "In 2004, we conducted a study in Piemonte (Italy), in order to describe incidence, treatment, hospitalizations and costs of herpes zoster (HZ), in population over 14 years of age. Twenty-four regional general practitioners, with 26,394 patients >14 years in charge (0.71% of the regional population), reported prospectively all diagnosed HZ cases. In addition, all regional hospital discharge records were reviewed. Forty-six HZ cases treated at home were reported, accounting for a total incidence of 1.74 cases/1000 population >14 years per year. HZ rate standardized by age on regional population 14 years older is 1.59/1000. The cost per observed home case was €136.06. The incidence of hospital admissions was 0.12/1000 inhabitants. The mean cost of hospitalized cases was €4082.59. These results contribute to depict the impact of HZ in the general population, and to provide background data for setting-up either mathematical models aimed to estimate the impact of vaccination on HZ, and the cost-benefit analyses of various preventive and therapeutic scenarios.",

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author = "{Di Legami}, Valeria and Gianino, {Maria Michela} and Atti, {Marta Ciofi Degli} and Marco Massari and Alessandro Migliardi and Tomba, {Gianpaolo Scalia} and Carla Zotti",

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AU - Massari, Marco

AU - Migliardi, Alessandro

AU - Tomba, Gianpaolo Scalia

AU - Zotti, Carla

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Epidemiology and costs of herpes zoster: Background data to estimate the impact of vaccination

Abstract

Keywords

ASJC Scopus subject areas

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