Abstract
Epidermal Growth Factor (EGF) stimulates the proliferation of epithelium both in organ culture and in vivo: the topical application of the factor to the burns of mice resulted in a marked hyperplasia. The epithelium rapidly regressed to its normal thickness: this phenomenon is accomplished by a histologic increase of ATP-ase, leucinoaminopeptidase, succinodehydrogenase in the epidermal cells. In this paper we reported that EGF accelerated the repair of burns in adult mice.
Translated title of the contribution | Enzymatic modifications of burned skin in mice after topical treatment with EGF |
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Original language | Italian |
Pages (from-to) | 419-425 |
Number of pages | 7 |
Journal | Chronica Dermatologica |
Volume | 8 |
Issue number | 3-4 |
Publication status | Published - 1977 |
ASJC Scopus subject areas
- Dermatology