TY - JOUR
T1 - Enterovirus D68-Associated Community-Acquired Pneumonia in the Pediatric Age Group
AU - Bosis, Samantha
AU - Esposito, Susanna
PY - 2017/3/1
Y1 - 2017/3/1
N2 - Purpose of Review: This review summarizes the current knowledge regarding the role of Enterovirus D68 (EV-D68) in community-acquired pneumonia (CAP) in children. Recent Findings: EV-D68 is an emergent viral pathogen. Since its first isolation in 1962 in California in four children suffering from CAP and bronchiolitis, EV-D68 has been rarely detected from respiratory specimens. However, recently, EV-D68 infection has raised concerns in the international community because of outbreaks in 2014 in the USA and the increased number of children with EV-D68-associated severe respiratory illnesses, including pneumonia, that have been reported in many other countries around the world. Summary: EV-D68 causes severe and life-threatening respiratory diseases in the pediatric population, particularly in children with underlying conditions such as prematurity or chronic diseases. Since no specific treatment or vaccinations are available for EV-D68 infections, greater surveillance as well as the use of sensitive and rapid diagnostic methods are essential to prevent and manage new outbreaks.
AB - Purpose of Review: This review summarizes the current knowledge regarding the role of Enterovirus D68 (EV-D68) in community-acquired pneumonia (CAP) in children. Recent Findings: EV-D68 is an emergent viral pathogen. Since its first isolation in 1962 in California in four children suffering from CAP and bronchiolitis, EV-D68 has been rarely detected from respiratory specimens. However, recently, EV-D68 infection has raised concerns in the international community because of outbreaks in 2014 in the USA and the increased number of children with EV-D68-associated severe respiratory illnesses, including pneumonia, that have been reported in many other countries around the world. Summary: EV-D68 causes severe and life-threatening respiratory diseases in the pediatric population, particularly in children with underlying conditions such as prematurity or chronic diseases. Since no specific treatment or vaccinations are available for EV-D68 infections, greater surveillance as well as the use of sensitive and rapid diagnostic methods are essential to prevent and manage new outbreaks.
KW - Children
KW - Community-acquired pneumonia
KW - Enterovirus D68
KW - EV-D68
KW - Respiratory distress
KW - Respiratory tract infections
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U2 - 10.1007/s11908-017-0567-8
DO - 10.1007/s11908-017-0567-8
M3 - Review article
AN - SCOPUS:85014459793
SN - 1523-3847
VL - 19
JO - Current Infectious Disease Reports
JF - Current Infectious Disease Reports
IS - 3
M1 - 12
ER -