Abstract
The lasting research on the endocannabinoid system (ECS) has now provided solid and convincing evidence that proves the detrimental effects of recreational drug abuse (a growing habit among teenagers) on fertility. Endocannabinoids (eCBs) affect reproductive events from gametogenesis to fertilization, from embryo implantation to the final outcome of pregnancy and, thus, they have been proposed as suitable biomarkers to predict the reproductive potential of male and female gametes in clinical practice. Novel tools for reproductive medicine are highly sought after, and here we report the latest findings on the impact of the ECS on fertility, demonstrating how basic research can be translated into new medical strategies.
Original language | English |
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Title of host publication | Endocannabinoids |
Publisher | Springer International Publishing |
Pages | 341-365 |
Number of pages | 25 |
ISBN (Print) | 9783319208251, 9783319208244 |
DOIs | |
Publication status | Published - Sept 25 2015 |
Keywords
- AEA Anandamide
- Biomarkers
- Endocannabinoid system
- Infertility
- Reproduction
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Neuroscience(all)
- Immunology and Microbiology(all)