Abstract
trans-Dihydrolisuride, a partial dopamine receptor agonist, was tested for its effects on chorea in a double-blind, crossover clinical study in 10 patients with Huntington's disease. In eight patients, a neurophysiological evaluation was also performed. No reduction in choreic movements or improvement in voluntary movement performance was observed. However, in some patients, there was a slight improvement in patient's alertness and a reduction of the movement reaction time.
| Original language | English |
|---|---|
| Pages (from-to) | 435-439 |
| Number of pages | 5 |
| Journal | Clinical Neuropharmacology |
| Volume | 12 |
| Issue number | 5 |
| Publication status | Published - 1989 |
Keywords
- chorea
- Terguride
ASJC Scopus subject areas
- Clinical Neurology
- Pharmacology (medical)
- Neuroscience(all)
- Pharmacology, Toxicology and Pharmaceutics(all)