TY - JOUR
T1 - Effects of gastroesophageal reflux disease in laryngeal carcinoma
AU - Bacciu, Andrea
AU - Mercante, G.
AU - Ingegnoli, A.
AU - Ferri, T.
AU - Muzzetto, P.
AU - Leandro, G.
AU - Di Mario, F.
AU - Bacciu, S.
PY - 2004/10
Y1 - 2004/10
N2 - Gastroesophageal reflux disease is associated with various otolaryngological disorders. The aim of this retrospective study was to determine the role of gastroesophageal reflux disease in the development of laryngeal squamous cell carcinoma (SCC) in non-smoking and non-drinking patients. The study population consisted of 36 consecutive non-smoking and non-drinking patients with histologically confirmed SCC of the larynx. As a control, a group of 125 lifetime non-smoking and non-drinking cancer-free subjects were selected. Patients with laryngeal cancer had a higher prevalence of gastroesophageal reflux disease than the control subjects (P <0.0001). Our results confirm the fact that gastroesophageal reflux disease in itself is associated with an increased risk of laryngeal cancer.
AB - Gastroesophageal reflux disease is associated with various otolaryngological disorders. The aim of this retrospective study was to determine the role of gastroesophageal reflux disease in the development of laryngeal squamous cell carcinoma (SCC) in non-smoking and non-drinking patients. The study population consisted of 36 consecutive non-smoking and non-drinking patients with histologically confirmed SCC of the larynx. As a control, a group of 125 lifetime non-smoking and non-drinking cancer-free subjects were selected. Patients with laryngeal cancer had a higher prevalence of gastroesophageal reflux disease than the control subjects (P <0.0001). Our results confirm the fact that gastroesophageal reflux disease in itself is associated with an increased risk of laryngeal cancer.
KW - Gastroesophageal reflux disease
KW - Laryngeal squamous cell carcinoma
KW - Oesophagogastroduodenoscopy
UR - http://www.scopus.com/inward/record.url?scp=4644285760&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=4644285760&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2273.2004.00851.x
DO - 10.1111/j.1365-2273.2004.00851.x
M3 - Article
C2 - 15373871
AN - SCOPUS:4644285760
SN - 0307-7772
VL - 29
SP - 545
EP - 548
JO - Clinical Otolaryngology and Allied Sciences
JF - Clinical Otolaryngology and Allied Sciences
IS - 5
ER -