Effects of dimethylformamide (dmf) on coagulation and platelet activity

Marcello Imbriani; Sergio Ghittori; Alberto Prestinoni; Patrizia Longoni; Giorgio Cascone; Gabriella Gamba

doi:10.1080/00039896.1986.9937415

Effects of dimethylformamide (dmf) on coagulation and platelet activity

Marcello Imbriani, Sergio Ghittori, Alberto Prestinoni, Patrizia Longoni, Giorgio Cascone, Gabriella Gamba

Research output: Contribution to journal › Article › peer-review

Abstract

The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m³, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

Original language	English
Pages (from-to)	90-93
Number of pages	4
Journal	Archives of Environmental Health
Volume	41
Issue number	2
DOIs	https://doi.org/10.1080/00039896.1986.9937415
Publication status	Published - 1986

ASJC Scopus subject areas

Health, Toxicology and Mutagenesis
Environmental Science(all)
Environmental Chemistry
Public Health, Environmental and Occupational Health

Access to Document

10.1080/00039896.1986.9937415

Cite this

@article{25f8c7627b994d13aacbbb4ba28f332a,

title = "Effects of dimethylformamide (dmf) on coagulation and platelet activity",

abstract = "The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.",

author = "Marcello Imbriani and Sergio Ghittori and Alberto Prestinoni and Patrizia Longoni and Giorgio Cascone and Gabriella Gamba",

year = "1986",

doi = "10.1080/00039896.1986.9937415",

language = "English",

volume = "41",

pages = "90--93",

journal = "Archives of Environmental Health",

issn = "0003-9896",

publisher = "Taylor and Francis Ltd.",

number = "2",

}

TY - JOUR

T1 - Effects of dimethylformamide (dmf) on coagulation and platelet activity

AU - Imbriani, Marcello

AU - Ghittori, Sergio

AU - Prestinoni, Alberto

AU - Longoni, Patrizia

AU - Cascone, Giorgio

AU - Gamba, Gabriella

PY - 1986

Y1 - 1986

N2 - The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

AB - The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

UR - http://www.scopus.com/inward/record.url?scp=0022510783&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022510783&partnerID=8YFLogxK

U2 - 10.1080/00039896.1986.9937415

DO - 10.1080/00039896.1986.9937415

M3 - Article

C2 - 3718008

AN - SCOPUS:0022510783

SN - 0003-9896

VL - 41

SP - 90

EP - 93

JO - Archives of Environmental Health

JF - Archives of Environmental Health

IS - 2

ER -

Effects of dimethylformamide (dmf) on coagulation and platelet activity

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this