Effects of dimethylformamide (dmf) on coagulation and platelet activity

Marcello Imbriani, Sergio Ghittori, Alberto Prestinoni, Patrizia Longoni, Giorgio Cascone, Gabriella Gamba

Research output: Contribution to journalArticlepeer-review


The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

Original languageEnglish
Pages (from-to)90-93
Number of pages4
JournalArchives of Environmental Health
Issue number2
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health


Dive into the research topics of 'Effects of dimethylformamide (dmf) on coagulation and platelet activity'. Together they form a unique fingerprint.

Cite this