Effectiveness of treat-to-target strategy for LDL-cholesterol control in type 2 diabetes: Post-hoc analysis of data from the MIND.IT study

Diego Ardigò, Olga Vaccaro, Franco Cavalot, Albarosa Angela Rivellese, Laura Franzini, Roberto Miccoli, Lidia Patti, Massimo Boemi, Mariella Trovati, Ivana Zavaroni

Research output: Contribution to journalArticlepeer-review

Abstract

Background: The paper presents a post-hoc analysis of the intensity of dyslipidaemia care operated in the first 2 years of Multiple-Intervention-in- type2-Diabetes.ITaly (MIND.IT) study. Design and methods: MIND.IT is a multicentric, randomized, two-parallel arm trial involving 1461 type 2 diabetic patients at high cardiovascular (CV) risk. The study compares the usual care (UC) of CV prevention with a multifactorial intensive care (IC) approach aiming at achieving target values for the main CV risk factors according to a step-wise treatto- target approach. Results: Proportion of patients on target for low-density lipoprotein cholesterol (LDL-C) was about 10% at baseline and increased significantly more with IC than UC (43 vs. 27%; p

Original languageEnglish
Pages (from-to)456-463
Number of pages8
JournalEuropean Journal of Preventive Cardiology
Volume21
Issue number4
DOIs
Publication statusPublished - 2014

Keywords

  • Cardiovascular
  • cholesterol
  • diabetes
  • intervention
  • lipid
  • statins
  • treatment

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Epidemiology
  • Medicine(all)

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