Effect of verapamil on allergen-induced asthma in patients with respiratory allergy

A. Miadonna; A. Tedeschi; E. Leggieri; M. Cottini; M. Restuccia; C. Bianchini

Effect of verapamil on allergen-induced asthma in patients with respiratory allergy

A. Miadonna, A. Tedeschi, E. Leggieri, M. Cottini, M. Restuccia, C. Bianchini

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.

Original language	English
Pages (from-to)	201-204
Number of pages	4
Journal	Annals of Allergy
Volume	51
Issue number	2 I
Publication status	Published - 1983

ASJC Scopus subject areas

Immunology and Allergy

Cite this

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abstract = "Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.",

author = "A. Miadonna and A. Tedeschi and E. Leggieri and M. Cottini and M. Restuccia and C. Bianchini",

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AU - Miadonna, A.

AU - Tedeschi, A.

AU - Leggieri, E.

AU - Cottini, M.

AU - Restuccia, M.

AU - Bianchini, C.

PY - 1983

Y1 - 1983

N2 - Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.

AB - Specific degranulation of mast cells and basophils depends upon transmembrane calcium flow. In the present studies the protective effect of the calcium-antagonist drug verapamil against allergen-induced asthma was assessed in eight atopic patients. The results of this study showed that verapamil, administered both orally or by aerosol, can prevent the specific bronchoconstriction.

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Effect of verapamil on allergen-induced asthma in patients with respiratory allergy

Abstract

ASJC Scopus subject areas

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