Abstract
To investigate bone mineral metabolism in insulin-dependent diabetes mellitus, serum osteocalcin, a marker of bone formation, was measured in 31 diabetic children at onset of disease and 15 days after metabolic improvement by insulin therapy. As a control group for osteocalcin levels we studied 31 healthy sex- and age-matched children. Mean values of serum osteocalcin at onset of diabetes were significantly lower than in control group (p
Original language | English |
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Pages (from-to) | 505-509 |
Number of pages | 5 |
Journal | Journal of Endocrinological Investigation |
Volume | 16 |
Issue number | 7 |
DOIs | |
Publication status | Published - 1993 |
Keywords
- adolescents
- children
- insulin-dependent diabetes mellitus
- Osteocalcin
- osteopenia
- parathyroid hormone
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism