EEG power modifications in obsessive-compulsive disorder during olfactory stimulation

Marco Locatelli, Laura Bellodi, Barbara Grassi, Silvio Scarone

Research output: Contribution to journalArticlepeer-review


Temporal lobe electroencephalogram (EEG) activity was quantitatively analyzed in obsessive-compulsive disorder (OCD) when subjects are at vest and during a temporal lobe activating procedure, i.e., olfactory stimulation. At rest with eyes closed, delta-1 and alpha-2 power differences were evident in OCD patients as compared with normal controls. During olfactory stimulation, differences between the patient and normal groups were detectable in the slower beta frequencies: Normal subjects showed a power increase, whereas OCD patients showed no modification or a slight decrease, Our results support previous findings of temporal lobe EEG abnormalities in OCD patients with an abnormal pattern of response to a temporal lobe activating procedure.

Original languageEnglish
Pages (from-to)326-331
Number of pages6
JournalBiological Psychiatry
Issue number5
Publication statusPublished - Mar 1 1996


  • Electroencephalogram (EEG)
  • Obsessive-compulsive disorder
  • Olfactory stimulation
  • Spectral analysis
  • Temporal lobe

ASJC Scopus subject areas

  • Biological Psychiatry


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