EEG, MRI and SPECT biomarkers evidence in prodromal alzheimer's disease

Research output: Chapter in Book/Report/Conference proceedingChapter


Background: Thinning of the temporo-parietal cortex is associated with mild cognitive impairment (MCI) due to Alzheimer's disease (AD). In AD patients, an increase in EEG upper/low alpha power ratio has been associated with MCI and with atrophy of the temporo-parietal brain areas. Moreover, subjects with a higher alpha3/alpha2 frequency power ratio showed a lower brain perfusion than low alpha3/alpha2 subjects. The two groups have significantly different hippocampal volume and a correlation with the theta frequency activity was found.

Original languageEnglish
Title of host publicationHorizons in Neuroscience Research
PublisherNova Science Publishers, Inc.
Number of pages28
ISBN (Print)9781634830140, 9781634829670
Publication statusPublished - Jul 1 2015

ASJC Scopus subject areas

  • Neuroscience(all)


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