EEG, MRI and SPECT biomarkers evidence in prodromal alzheimer's disease

D. V. Moretti

EEG, MRI and SPECT biomarkers evidence in prodromal alzheimer's disease

Centro San Giovanni di Dio - Fatebenefratelli

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Background: Thinning of the temporo-parietal cortex is associated with mild cognitive impairment (MCI) due to Alzheimer's disease (AD). In AD patients, an increase in EEG upper/low alpha power ratio has been associated with MCI and with atrophy of the temporo-parietal brain areas. Moreover, subjects with a higher alpha3/alpha2 frequency power ratio showed a lower brain perfusion than low alpha3/alpha2 subjects. The two groups have significantly different hippocampal volume and a correlation with the theta frequency activity was found.

Original language	English
Title of host publication	Horizons in Neuroscience Research
Publisher	Nova Science Publishers, Inc.
Pages	35-62
Number of pages	28
Volume	21
ISBN (Print)	9781634830140, 9781634829670
Publication status	Published - Jul 1 2015

ASJC Scopus subject areas

Neuroscience(all)

Cite this

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AB - Background: Thinning of the temporo-parietal cortex is associated with mild cognitive impairment (MCI) due to Alzheimer's disease (AD). In AD patients, an increase in EEG upper/low alpha power ratio has been associated with MCI and with atrophy of the temporo-parietal brain areas. Moreover, subjects with a higher alpha3/alpha2 frequency power ratio showed a lower brain perfusion than low alpha3/alpha2 subjects. The two groups have significantly different hippocampal volume and a correlation with the theta frequency activity was found.

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EEG, MRI and SPECT biomarkers evidence in prodromal alzheimer's disease

Abstract

ASJC Scopus subject areas

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