Do hemoglobin and hemocyanin impair Schistosoma killing by NO?

Paolo Ascenzi, Mauro Fasano, Luigi Gradoni

Research output: Contribution to journalArticlepeer-review


Nitric oxide (NO) possesses antiparasitic effects on both Protozoa and Metazoa in definitive and intermediate hosts as well as in vectors. Here, we postulate that hemoglobin and hemocyanin may impair Schistosoma killing by NO in the definitive and intermediate hosts. Interestingly, hemoglobin, myoglobin, and neuroglobin may protect Plasmodium and Trypanosoma from the antiparasitic effects of NO.

Original languageEnglish
Pages (from-to)287-288
Number of pages2
JournalIUBMB Life
Issue number6
Publication statusPublished - Jun 2002


  • Antiparasitic effect of nitric oxide
  • Hemocyanin
  • Hemoglobin
  • Nitric oxide scavenging
  • Schistosoma

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Cell Biology


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