Distribution and significance of the smooth muscle component in polyps of the large intestine

Ezio Fulcheri; Patrizia Baracchini; Gabriella Lapertosa; Gianni Bussolati

doi:10.1016/S0046-8177(88)80007-8

Distribution and significance of the smooth muscle component in polyps of the large intestine

Ezio Fulcheri, Patrizia Baracchini, Gabriella Lapertosa, Gianni Bussolati

Istituto "Giannina Gaslini"

Research output: Contribution to journal › Article › peer-review

Abstract

Immunocytochemical staining for alpha smooth muscle actin specifically reveals the distribution of the muscularis mucosae and pericryptal intramucosal smooth muscle fibers in the normal mucosa and polyps of the large intestine. In the latter, the muscular component is hyperplastic, especially in pedunculated polyps, which display a thick "muscular zone" at the top of the stalk. The diagnostic (and prognostic) significance of the distribution pattern of the muscular component in polyps, and in "early invasion" cases, is discussed.

Original language	English
Pages (from-to)	922-927
Number of pages	6
Journal	Human Pathology
Volume	19
Issue number	8
DOIs	https://doi.org/10.1016/S0046-8177(88)80007-8
Publication status	Published - 1988

Keywords

actin
carcinomas
immunocytochemistry
intestine
polyps

ASJC Scopus subject areas

Pathology and Forensic Medicine

Access to Document

10.1016/S0046-8177(88)80007-8

Cite this

@article{6b596a7aa6af47edb385d1460b26bad9,

title = "Distribution and significance of the smooth muscle component in polyps of the large intestine",

abstract = "Immunocytochemical staining for alpha smooth muscle actin specifically reveals the distribution of the muscularis mucosae and pericryptal intramucosal smooth muscle fibers in the normal mucosa and polyps of the large intestine. In the latter, the muscular component is hyperplastic, especially in pedunculated polyps, which display a thick {"}muscular zone{"} at the top of the stalk. The diagnostic (and prognostic) significance of the distribution pattern of the muscular component in polyps, and in {"}early invasion{"} cases, is discussed.",

keywords = "actin, carcinomas, immunocytochemistry, intestine, polyps",

author = "Ezio Fulcheri and Patrizia Baracchini and Gabriella Lapertosa and Gianni Bussolati",

year = "1988",

doi = "10.1016/S0046-8177(88)80007-8",

language = "English",

volume = "19",

pages = "922--927",

journal = "Human Pathology",

issn = "0046-8177",

publisher = "W.B. Saunders Ltd",

number = "8",

}

TY - JOUR

T1 - Distribution and significance of the smooth muscle component in polyps of the large intestine

AU - Fulcheri, Ezio

AU - Baracchini, Patrizia

AU - Lapertosa, Gabriella

AU - Bussolati, Gianni

PY - 1988

Y1 - 1988

N2 - Immunocytochemical staining for alpha smooth muscle actin specifically reveals the distribution of the muscularis mucosae and pericryptal intramucosal smooth muscle fibers in the normal mucosa and polyps of the large intestine. In the latter, the muscular component is hyperplastic, especially in pedunculated polyps, which display a thick "muscular zone" at the top of the stalk. The diagnostic (and prognostic) significance of the distribution pattern of the muscular component in polyps, and in "early invasion" cases, is discussed.

AB - Immunocytochemical staining for alpha smooth muscle actin specifically reveals the distribution of the muscularis mucosae and pericryptal intramucosal smooth muscle fibers in the normal mucosa and polyps of the large intestine. In the latter, the muscular component is hyperplastic, especially in pedunculated polyps, which display a thick "muscular zone" at the top of the stalk. The diagnostic (and prognostic) significance of the distribution pattern of the muscular component in polyps, and in "early invasion" cases, is discussed.

KW - actin

KW - carcinomas

KW - immunocytochemistry

KW - intestine

KW - polyps

UR - http://www.scopus.com/inward/record.url?scp=0023740203&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023740203&partnerID=8YFLogxK

U2 - 10.1016/S0046-8177(88)80007-8

DO - 10.1016/S0046-8177(88)80007-8

M3 - Article

C2 - 3402981

AN - SCOPUS:0023740203

SN - 0046-8177

VL - 19

SP - 922

EP - 927

JO - Human Pathology

JF - Human Pathology

IS - 8

ER -

Distribution and significance of the smooth muscle component in polyps of the large intestine

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this