Deterioration of Lung Function in a Pig Model of Uncontrolled Cardiac Death

B. Safaee Fakhr; D. Dondossola; M. Cavenago; M. Zanetti; S. Gatti; L. Gattinoni; F. Valenza

doi:10.1016/j.transproceed.2015.12.046

Deterioration of Lung Function in a Pig Model of Uncontrolled Cardiac Death

B. Safaee Fakhr, D. Dondossola, M. Cavenago, M. Zanetti, S. Gatti, L. Gattinoni, F. Valenza

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction Uncontrolled donors after circulatory determination of death (uDCDD) represent a yet unexplored pool of organs potentially available for transplantation. The aims of this study were to validate a protocol of cardiac death in the pig and to investigate lung function during the process. Materials and Methods Cardiac death was induced in preanesthetized animals with an injection of 600 mg propofol; once systolic blood pressure was 2/FiO₂ decreased from 442 ± 31 mm Hg at baseline to 63 ± 36 at end-CPR (P

Original language	English
Pages (from-to)	431-434
Number of pages	4
Journal	Transplantation Proceedings
Volume	48
Issue number	2
DOIs	https://doi.org/10.1016/j.transproceed.2015.12.046
Publication status	Published - Mar 1 2016

ASJC Scopus subject areas

Surgery
Transplantation

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abstract = "Introduction Uncontrolled donors after circulatory determination of death (uDCDD) represent a yet unexplored pool of organs potentially available for transplantation. The aims of this study were to validate a protocol of cardiac death in the pig and to investigate lung function during the process. Materials and Methods Cardiac death was induced in preanesthetized animals with an injection of 600 mg propofol; once systolic blood pressure was 2/FiO2 decreased from 442 ± 31 mm Hg at baseline to 63 ± 36 at end-CPR (P ",

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AU - Cavenago, M.

AU - Zanetti, M.

AU - Gatti, S.

AU - Gattinoni, L.

AU - Valenza, F.

PY - 2016/3/1

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AB - Introduction Uncontrolled donors after circulatory determination of death (uDCDD) represent a yet unexplored pool of organs potentially available for transplantation. The aims of this study were to validate a protocol of cardiac death in the pig and to investigate lung function during the process. Materials and Methods Cardiac death was induced in preanesthetized animals with an injection of 600 mg propofol; once systolic blood pressure was 2/FiO2 decreased from 442 ± 31 mm Hg at baseline to 63 ± 36 at end-CPR (P

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Deterioration of Lung Function in a Pig Model of Uncontrolled Cardiac Death

Abstract

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