Abstract
We report the behavioural abnormalities, neuroimaging, and neuropsychological results of a 62-year-old patient, IP, who shows a clinical profile that fulfils all characteristics of dementia of frontal lobe type. The patient has been followed up over 5 years with psychometric testing. Comparing her cognitive profiles across examinations, her performance was substantially unchanged apart from behavioural disturbances and performance on frontal tasks which showed a progressive worsening. MRI finding evidenced marked ventricular enlargement, prevalent frontal atrophy and hypertrophy of the genus of corpus callosum. SPECT investigation showed a considerable reduction of cerebral blood flow in the mesial parts of the frontal lobes, in the lateral surface of the right fronto-parietal lobe, and hypo-perfusion in the right thalamic area. The results are discussed with reference to the features (clinical and neuropsychological) which distinguish different profiles of dementia.
| Original language | English |
|---|---|
| Pages (from-to) | 155-160 |
| Number of pages | 6 |
| Journal | Dementia |
| Volume | 7 |
| Issue number | 3 |
| Publication status | Published - 1996 |
Keywords
- Behavioural disorders
- Demential of frontal lobe type
- Frontotemporal dementia
- SPECT neuropsychology
ASJC Scopus subject areas
- Geriatrics and Gerontology
- Neuropsychology and Physiological Psychology