TY - JOUR
T1 - Delivery of online adaptive magnetic resonance guided radiotherapy based on isodose boundaries
AU - Votta, Claudio
AU - Cusumano, Davide
AU - Boldrini, Luca
AU - Dinapoli, Nicola
AU - Placidi, Lorenzo
AU - Turco, Gabriele
AU - Antonelli, Marco Valerio
AU - Pollutri, Veronica
AU - Romano, Angela
AU - Indovina, Luca
AU - Valentini, Vincenzo
N1 - Funding Information:
We would like to thank Franziska M. Lohmeyer, PhD, Fondazione Policlinico Universitario A. Gemelli IRCCS, for her support revising our manuscript. This paper is part of a special issue that contains contributions originally submitted to the scientific meeting MR in RT, which was planned to take place 05/2020, organized by the German Research Center (DKFZ) in Heidelberg.
Publisher Copyright:
© 2021 The Authors
PY - 2021/4
Y1 - 2021/4
N2 - Magnetic Resonance-guided Radiotherapy (MRgRT) allows direct monitoring of treated volumes. The aim of this study was to investigate the feasibility of a new gating strategy consisting in using an isodose as boundary. Forty-four patients treated for thoracic and abdominal lesions using MRgRT were enrolled. The accuracy of the new strategy was compared to the conventional one in terms of area improvement available for gating without compromising target coverage. A mean increase of 24% for lung, 15% for liver and 11% for pancreas was observed, demonstrating how the new method can be useful in challenging situations with low dose conformality.
AB - Magnetic Resonance-guided Radiotherapy (MRgRT) allows direct monitoring of treated volumes. The aim of this study was to investigate the feasibility of a new gating strategy consisting in using an isodose as boundary. Forty-four patients treated for thoracic and abdominal lesions using MRgRT were enrolled. The accuracy of the new strategy was compared to the conventional one in terms of area improvement available for gating without compromising target coverage. A mean increase of 24% for lung, 15% for liver and 11% for pancreas was observed, demonstrating how the new method can be useful in challenging situations with low dose conformality.
KW - Dosimetric boundary
KW - Image guidance gating
KW - MR-guided radiotherapy
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U2 - 10.1016/j.phro.2021.05.005
DO - 10.1016/j.phro.2021.05.005
M3 - Article
AN - SCOPUS:85107708238
SN - 2405-6316
VL - 18
SP - 78
EP - 81
JO - Physics and Imaging in Radiation Oncology
JF - Physics and Imaging in Radiation Oncology
ER -