TY - JOUR
T1 - Delayed infection, late tonsillectomy or adenoidectomy and adult leukaemia
T2 - A case-control study
AU - Vineis, P.
AU - Miligi, L.
AU - Crosignani, P.
AU - Davico, L.
AU - Fontana, A.
AU - Masala, G.
AU - Nanni, O.
AU - Ramazzotti, V.
AU - Rodella, S.
AU - Stagnaro, E.
AU - Tumino, R.
AU - Viganò, C.
AU - Vindigni, C.
AU - Costantini, A. S.
PY - 2003/1/13
Y1 - 2003/1/13
N2 - In a population-based case-control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1-16.2). We propose that late infection is a proliferative stimulus for B-cells.
AB - In a population-based case-control study among adults in Italy, of 261 lymphoid and 313 myeloid leukaemias and 1718 controls, a later age at adenoidectomy and tonsillectomy (after age 10years) increased considerably the risk of lymphocytic (but not myeloid) leukaemia (odds ratio 4.2, 95% confidence interval 1.1-16.2). We propose that late infection is a proliferative stimulus for B-cells.
UR - http://www.scopus.com/inward/record.url?scp=0037434416&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037434416&partnerID=8YFLogxK
U2 - 10.1038/sj.bjc.6600689
DO - 10.1038/sj.bjc.6600689
M3 - Article
C2 - 12556958
AN - SCOPUS:0037434416
SN - 0007-0920
VL - 88
SP - 47
EP - 49
JO - British Journal of Cancer
JF - British Journal of Cancer
IS - 1
ER -