Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

H. Bulluck, Y.Y. Go, G. Crimi, A.J. Ludman, S. Rosmini, A. Abdel-Gadir, A.N. Bhuva, T.A. Treibel, M. Fontana, S. Pica, C. Raineri, A. Sirker, A.S. Herrey, C. Manisty, A. Groves, J.C. Moon, D.J. Hausenloy

Research output: Contribution to journalArticlepeer-review


Background: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. Methods: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined. Secondly, in 146 reperfused STEMI patients, receiver operator characteristic curve analyses for predicting LVEF
Original languageEnglish
JournalJournal of Cardiovascular Magnetic Resonance
Issue number1
Publication statusPublished - 2017


  • infarct size, microvascular obstruction
  • LV ejection fraction
  • LV end-diastolic volume
  • LV end-systolic volume
  • LV remodeling, trabeculae and papillary muscles
  • ST-segment elevation myocardial infarction
  • adult
  • Article
  • cardiovascular magnetic resonance
  • clinical article
  • female
  • follow up
  • heart left ventricle ejection fraction
  • heart left ventricle enddiastolic volume
  • heart left ventricle endsystolic volume
  • heart left ventricle mass
  • heart muscle reperfusion
  • heart ventricle remodeling
  • human
  • male
  • observer variation
  • sensitivity and specificity
  • ST segment elevation myocardial infarction
  • aged
  • area under the curve
  • cine magnetic resonance imaging
  • diagnostic imaging
  • heart left ventricle function
  • heart stroke volume
  • middle aged
  • pathophysiology
  • percutaneous coronary intervention
  • predictive value
  • receiver operating characteristic
  • reproducibility
  • time factor
  • treatment outcome
  • Aged
  • Area Under Curve
  • Female
  • Humans
  • Magnetic Resonance Imaging, Cine
  • Male
  • Middle Aged
  • Observer Variation
  • Percutaneous Coronary Intervention
  • Predictive Value of Tests
  • Reproducibility of Results
  • ROC Curve
  • ST Elevation Myocardial Infarction
  • Stroke Volume
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left
  • Ventricular Remodeling


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