Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

H. Bulluck; Y.Y. Go; G. Crimi; A.J. Ludman; S. Rosmini; A. Abdel-Gadir; A.N. Bhuva; T.A. Treibel; M. Fontana; S. Pica; C. Raineri; A. Sirker; A.S. Herrey; C. Manisty; A. Groves; J.C. Moon; D.J. Hausenloy

doi:10.1186/s12968-017-0343-9

Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

H. Bulluck, Y.Y. Go, G. Crimi, A.J. Ludman, S. Rosmini, A. Abdel-Gadir, A.N. Bhuva, T.A. Treibel, M. Fontana, S. Pica, C. Raineri, A. Sirker, A.S. Herrey, C. Manisty, A. Groves, J.C. Moon, D.J. Hausenloy

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. Methods: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined. Secondly, in 146 reperfused STEMI patients, receiver operator characteristic curve analyses for predicting LVEF

Original language	English
Journal	Journal of Cardiovascular Magnetic Resonance
Volume	19
Issue number	1
DOIs	https://doi.org/10.1186/s12968-017-0343-9
Publication status	Published - 2017

Keywords

infarct size, microvascular obstruction
LV ejection fraction
LV end-diastolic volume
LV end-systolic volume
LV remodeling, trabeculae and papillary muscles
ST-segment elevation myocardial infarction
adult
Article
cardiovascular magnetic resonance
clinical article
female
follow up
heart left ventricle ejection fraction
heart left ventricle enddiastolic volume
heart left ventricle endsystolic volume
heart left ventricle mass
heart muscle reperfusion
heart ventricle remodeling
human
male
observer variation
sensitivity and specificity
ST segment elevation myocardial infarction
aged
area under the curve
cine magnetic resonance imaging
diagnostic imaging
heart left ventricle function
heart stroke volume
middle aged
pathophysiology
percutaneous coronary intervention
predictive value
receiver operating characteristic
reproducibility
time factor
treatment outcome
Aged
Area Under Curve
Female
Humans
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Observer Variation
Percutaneous Coronary Intervention
Predictive Value of Tests
Reproducibility of Results
ROC Curve
ST Elevation Myocardial Infarction
Stroke Volume
Time Factors
Treatment Outcome
Ventricular Function, Left
Ventricular Remodeling

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10.1186/s12968-017-0343-9

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85014992281&doi=10.1186%2fs12968-017-0343-9&partnerID=40&md5=eb4e295d31fcc761e2fb4b0e79c081eb

Cite this

Bulluck, H., Go, Y. Y., Crimi, G., Ludman, A. J., Rosmini, S., Abdel-Gadir, A., Bhuva, A. N., Treibel, T. A., Fontana, M., Pica, S., Raineri, C., Sirker, A., Herrey, A. S., Manisty, C., Groves, A., Moon, J. C., & Hausenloy, D. J. (2017). Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance. Journal of Cardiovascular Magnetic Resonance, 19(1). https://doi.org/10.1186/s12968-017-0343-9

Bulluck, H, Go, YY, Crimi, G, Ludman, AJ, Rosmini, S, Abdel-Gadir, A, Bhuva, AN, Treibel, TA, Fontana, M, Pica, S , Raineri, C, Sirker, A, Herrey, AS, Manisty, C, Groves, A, Moon, JC & Hausenloy, DJ 2017, 'Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance', Journal of Cardiovascular Magnetic Resonance, vol. 19, no. 1. https://doi.org/10.1186/s12968-017-0343-9

@article{b3e4b06ac54b483eb2227decd05a9a1e,

title = "Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance",

abstract = "Background: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. Methods: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined. Secondly, in 146 reperfused STEMI patients, receiver operator characteristic curve analyses for predicting LVEF ",

keywords = "infarct size, microvascular obstruction, LV ejection fraction, LV end-diastolic volume, LV end-systolic volume, LV remodeling, trabeculae and papillary muscles, ST-segment elevation myocardial infarction, adult, Article, cardiovascular magnetic resonance, clinical article, female, follow up, heart left ventricle ejection fraction, heart left ventricle enddiastolic volume, heart left ventricle endsystolic volume, heart left ventricle mass, heart muscle reperfusion, heart ventricle remodeling, human, male, observer variation, sensitivity and specificity, ST segment elevation myocardial infarction, aged, area under the curve, cine magnetic resonance imaging, diagnostic imaging, heart left ventricle function, heart stroke volume, middle aged, pathophysiology, percutaneous coronary intervention, predictive value, receiver operating characteristic, reproducibility, time factor, treatment outcome, Aged, Area Under Curve, Female, Humans, Magnetic Resonance Imaging, Cine, Male, Middle Aged, Observer Variation, Percutaneous Coronary Intervention, Predictive Value of Tests, Reproducibility of Results, ROC Curve, ST Elevation Myocardial Infarction, Stroke Volume, Time Factors, Treatment Outcome, Ventricular Function, Left, Ventricular Remodeling",

author = "H. Bulluck and Y.Y. Go and G. Crimi and A.J. Ludman and S. Rosmini and A. Abdel-Gadir and A.N. Bhuva and T.A. Treibel and M. Fontana and S. Pica and C. Raineri and A. Sirker and A.S. Herrey and C. Manisty and A. Groves and J.C. Moon and D.J. Hausenloy",

note = "Cited By :5 Export Date: 2 March 2018 CODEN: JCMRF Correspondence Address: Bulluck, H.; Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College LondonUnited Kingdom; email: h.bulluck@gmail.com References: Westman, P.C., Lipinski, M.J., Luger, D., Waksman, R., Bonow, R.O., Wu, E., Epstein, S.E., Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction (2016) J Am Coll Cardiol, 67, pp. 2050-2060. , 27126533; Cheng, S., Vasan, R.S., Advances in the epidemiology of heart failure and left ventricular remodeling (2011) Circulation, 124, pp. e516-519. , 22083151 3621875; St John Sutton, M., Pfeffer, M.A., Plappert, T., Rouleau, J.L., Moye, L.A., Dagenais, G.R., Lamas, G.A., Goldman, S., Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril (1994) Circulation, 89, pp. 68-75. , 1:STN:280:DyaK2c7gvFSltA%3D%3D 8281697; Hellawell, J.L., Margulies, K.B., Myocardial reverse remodeling (2012) Cardiovasc Ther, 30, pp. 172-181. , 1:CAS:528:DC%2BC38XhtVClsLnI 21108773; Schulz-Menger, J., Bluemke, D.A., Bremerich, J., Flamm, S.D., Fogel, M.A., Friedrich, M.G., Kim, R.J., Pennell, D.J., Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) board of trustees task force on standardized post processing (2013) J Cardiovasc Magn Reson, 15, p. 35. , 23634753 3695769; Grothues, F., Smith, G.C., Moon, J.C., Bellenger, N.G., Collins, P., Klein, H.U., Pennell, D.J., Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy (2002) Am J Cardiol, 90, pp. 29-34. , 12088775; Hundley, W.G., Bluemke, D.A., Finn, J.P., Flamm, S.D., Fogel, M.A., Friedrich, M.G., Ho, V.B., Kramer, C.M., ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents (2010) Circulation, 121, pp. 2462-2508. , American College of Cardiology Foundation Task Force on Expert Consensus D; Bolognese, L., Cerisano, G., Buonamici, P., Santini, A., Santoro, G.M., Antoniucci, D., Fazzini, P.F., Influence of infarct-zone viability on left ventricular remodeling after acute myocardial infarction (1997) Circulation, 96, pp. 3353-3359. , 1:STN:280:DyaK1c%2FlslWisQ%3D%3D 9396427; Cerisano, G., Bolognese, L., Carrabba, N., Buonamici, P., Santoro, G.M., Antoniucci, D., Santini, A., Fazzini, P.F., Doppler-derived mitral deceleration time: An early strong predictor of left ventricular remodeling after reperfused anterior acute myocardial infarction (1999) Circulation, 99, pp. 230-236. , 1:STN:280:DyaK1M7htVOhtA%3D%3D 9892588; Yu, C.M., Bleeker, G.B., Fung, J.W., Schalij, M.J., Zhang, Q., Van Der Wall, E.E., Chan, Y.S., Bax, J.J., Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy (2005) Circulation, 112, pp. 1580-1586. , 16144994; Symons, R., Masci, P.G., Francone, M., Claus, P., Barison, A., Carbone, I., Agati, L., Bogaert, J., Impact of active smoking on myocardial infarction severity in reperfused ST-segment elevation myocardial infarction patients: the smoker's paradox revisited (2016) Eur Heart J., 37, pp. 2756-2764. , 26804461; Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M.C., Watkins, S., Pathophysiology of LV remodeling in survivors of STEMI: Inflammation, remote myocardium, and prognosis (2015) JACC Cardiovasc Imaging, 8, pp. 779-789. , 26093923 4509710; Bodi, V., Monmeneu, J.V., Ortiz-Perez, J.T., Lopez-Lereu, M.P., Bonanad, C., Husser, O., Minana, G., Forteza, M.J., Prediction of reverse remodeling at cardiac MR imaging soon after first ST-segment-elevation myocardial infarction: Results of a large prospective registry (2016) Radiology, 278, pp. 54-63. , 26348232; Larose, E., Rodes-Cabau, J., Pibarot, P., Rinfret, S., Proulx, G., Nguyen, C.M., Dery, J.P., Noel, B., Predicting late myocardial recovery and outcomes in the early hours of ST-segment elevation myocardial infarction traditional measures compared with microvascular obstruction, salvaged myocardium, and necrosis characteristics by cardiovascular magnetic resonance (2010) J Am Coll Cardiol, 55, pp. 2459-2469. , 20510213; Cheong, B.Y., Muthupillai, R., Wilson, J.M., Sung, A., Huber, S., Amin, S., Elayda, M.A., Flamm, S.D., Prognostic significance of delayed-enhancement magnetic resonance imaging: Survival of 857 patients with and without left ventricular dysfunction (2009) Circulation, 120, pp. 2069-2076. , 19901193; Ludman, A.J., Yellon, D.M., Hasleton, J., Ariti, C., Babu, G.G., Boston-Griffiths, E., Venugopal, V., Swanton, H., Effect of erythropoietin as an adjunct to primary percutaneous coronary intervention: A randomised controlled clinical trial (2011) Heart, 97, pp. 1560-1565. , 1:CAS:528:DC%2BC3MXhtlKjtb3M 21900585; Crimi, G., Pica, S., Raineri, C., Bramucci, E., De Ferrari, G.M., Klersy, C., Ferlini, M., Romeo, M., Remote ischemic post-conditioning of the lower limb during primary percutaneous coronary intervention safely reduces enzymatic infarct size in anterior myocardial infarction: A randomized controlled trial (2013) JACC Cardiovasc Interv, 6, pp. 1055-1063. , 24156966; Bulluck, H., White, S.K., Frohlich, G.M., Casson, S.G., O'Meara, C., Newton, A., Nicholas, J., Sirker, A., Quantifying the area at risk in reperfused ST-segment-elevation myocardial infarction patients using hybrid cardiac positron emission tomography-magnetic resonance imaging (2016) Circ Cardiovasc Imaging, 9, p. e003900. , 26926269 4826603; Bulluck, H., Rosmini, S., Abdel-Gadir, A., White, S.K., Bhuva, A.N., Treibel, T.A., Fontana, M., Ramlall, M., Automated extracellular volume fraction mapping provides insights into the pathophysiology of left ventricular remodeling post-reperfused ST-elevation myocardial infarction (2016) J Am Heart Assoc, 5, p. e003555. , 27402229 5015393; Bulluck, H., Rosmini, S., Abdel-Gadir, A., Bhuva, A.N., Treibel, T.A., Fontana, M., Weinmann, S., Manisty, C., Impact of microvascular obstruction on semiautomated techniques for quantifying acute and chronic myocardial infarction by cardiovascular magnetic resonance (2016) Open Heart, 3, p. e000535. , 28008358 5174824; Bulluck, H., Rosmini, S., Abdel-Gadir, A., White, S.K., Bhuva, A.N., Treibel, T.A., Fontana, M., Sirker, A., Residual Myocardial Iron Following Intramyocardial Hemorrhage During the Convalescent Phase of Reperfused ST-Segment-Elevation Myocardial Infarction and Adverse Left Ventricular Remodeling (2016) Circ Cardiovasc Imaging., 9. , e004940 27894068 5068185; Thavendiranathan, P., Grant, A.D., Negishi, T., Plana, J.C., Popovic, Z.B., Marwick, T.H., Reproducibility of echocardiographic techniques for sequential assessment of left ventricular ejection fraction and volumes: Application to patients undergoing cancer chemotherapy (2013) J Am Coll Cardiol, 61, pp. 77-84. , 23199515; Chuang, M.L., Gona, P., Hautvast, G.L., Salton, C.J., Blease, S.J., Yeon, S.B., Breeuwer, M., Manning, W.J., Correlation of trabeculae and papillary muscles with clinical and cardiac characteristics and impact on CMR measures of LV anatomy and function (2012) JACC Cardiovasc Imaging, 5, pp. 1115-1123. , 23153911 3502069; Weinsaft, J.W., Cham, M.D., Janik, M., Min, J.K., Henschke, C.I., Yankelevitz, D.F., Devereux, R.B., Left ventricular papillary muscles and trabeculae are significant determinants of cardiac MRI volumetric measurements: Effects on clinical standards in patients with advanced systolic dysfunction (2008) Int J Cardiol, 126, pp. 359-365. , 17698216; Kozor, R., Callaghan, F., Tchan, M., Hamilton-Craig, C., Figtree, G.A., Grieve, S.M., A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease (2015) J Cardiovasc Magn Reson, 17, p. 22. , 25890002 4335368; Orn, S., Manhenke, C., Greve, O.J., Larsen, A.I., Bonarjee, V.V., Edvardsen, T., Dickstein, K., Microvascular obstruction is a major determinant of infarct healing and subsequent left ventricular remodelling following primary percutaneous coronary intervention (2009) Eur Heart J, 30, pp. 1978-1985. , 19502624; Hamirani, Y.S., Wong, A., Kramer, C.M., Salerno, M., Effect of microvascular obstruction and intramyocardial hemorrhage by CMR on LV remodeling and outcomes after myocardial infarction: A systematic review and meta-analysis (2014) JACC Cardiovasc Imaging, 7, pp. 940-952. , 25212800 4301583",

year = "2017",

doi = "10.1186/s12968-017-0343-9",

language = "English",

volume = "19",

journal = "Journal of Cardiovascular Magnetic Resonance",

issn = "1097-6647",

publisher = "BioMed Central Ltd.",

number = "1",

}

TY - JOUR

T1 - Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

AU - Bulluck, H.

AU - Go, Y.Y.

AU - Crimi, G.

AU - Ludman, A.J.

AU - Rosmini, S.

AU - Abdel-Gadir, A.

AU - Bhuva, A.N.

AU - Treibel, T.A.

AU - Fontana, M.

AU - Pica, S.

AU - Raineri, C.

AU - Sirker, A.

AU - Herrey, A.S.

AU - Manisty, C.

AU - Groves, A.

AU - Moon, J.C.

AU - Hausenloy, D.J.

N1 - Cited By :5 Export Date: 2 March 2018 CODEN: JCMRF Correspondence Address: Bulluck, H.; Hatter Cardiovascular Institute, Institute of Cardiovascular Science, University College LondonUnited Kingdom; email: h.bulluck@gmail.com References: Westman, P.C., Lipinski, M.J., Luger, D., Waksman, R., Bonow, R.O., Wu, E., Epstein, S.E., Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction (2016) J Am Coll Cardiol, 67, pp. 2050-2060. , 27126533; Cheng, S., Vasan, R.S., Advances in the epidemiology of heart failure and left ventricular remodeling (2011) Circulation, 124, pp. e516-519. , 22083151 3621875; St John Sutton, M., Pfeffer, M.A., Plappert, T., Rouleau, J.L., Moye, L.A., Dagenais, G.R., Lamas, G.A., Goldman, S., Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril (1994) Circulation, 89, pp. 68-75. , 1:STN:280:DyaK2c7gvFSltA%3D%3D 8281697; Hellawell, J.L., Margulies, K.B., Myocardial reverse remodeling (2012) Cardiovasc Ther, 30, pp. 172-181. , 1:CAS:528:DC%2BC38XhtVClsLnI 21108773; Schulz-Menger, J., Bluemke, D.A., Bremerich, J., Flamm, S.D., Fogel, M.A., Friedrich, M.G., Kim, R.J., Pennell, D.J., Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) board of trustees task force on standardized post processing (2013) J Cardiovasc Magn Reson, 15, p. 35. , 23634753 3695769; Grothues, F., Smith, G.C., Moon, J.C., Bellenger, N.G., Collins, P., Klein, H.U., Pennell, D.J., Comparison of interstudy reproducibility of cardiovascular magnetic resonance with two-dimensional echocardiography in normal subjects and in patients with heart failure or left ventricular hypertrophy (2002) Am J Cardiol, 90, pp. 29-34. , 12088775; Hundley, W.G., Bluemke, D.A., Finn, J.P., Flamm, S.D., Fogel, M.A., Friedrich, M.G., Ho, V.B., Kramer, C.M., ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents (2010) Circulation, 121, pp. 2462-2508. , American College of Cardiology Foundation Task Force on Expert Consensus D; Bolognese, L., Cerisano, G., Buonamici, P., Santini, A., Santoro, G.M., Antoniucci, D., Fazzini, P.F., Influence of infarct-zone viability on left ventricular remodeling after acute myocardial infarction (1997) Circulation, 96, pp. 3353-3359. , 1:STN:280:DyaK1c%2FlslWisQ%3D%3D 9396427; Cerisano, G., Bolognese, L., Carrabba, N., Buonamici, P., Santoro, G.M., Antoniucci, D., Santini, A., Fazzini, P.F., Doppler-derived mitral deceleration time: An early strong predictor of left ventricular remodeling after reperfused anterior acute myocardial infarction (1999) Circulation, 99, pp. 230-236. , 1:STN:280:DyaK1M7htVOhtA%3D%3D 9892588; Yu, C.M., Bleeker, G.B., Fung, J.W., Schalij, M.J., Zhang, Q., Van Der Wall, E.E., Chan, Y.S., Bax, J.J., Left ventricular reverse remodeling but not clinical improvement predicts long-term survival after cardiac resynchronization therapy (2005) Circulation, 112, pp. 1580-1586. , 16144994; Symons, R., Masci, P.G., Francone, M., Claus, P., Barison, A., Carbone, I., Agati, L., Bogaert, J., Impact of active smoking on myocardial infarction severity in reperfused ST-segment elevation myocardial infarction patients: the smoker's paradox revisited (2016) Eur Heart J., 37, pp. 2756-2764. , 26804461; Carrick, D., Haig, C., Rauhalammi, S., Ahmed, N., Mordi, I., McEntegart, M., Petrie, M.C., Watkins, S., Pathophysiology of LV remodeling in survivors of STEMI: Inflammation, remote myocardium, and prognosis (2015) JACC Cardiovasc Imaging, 8, pp. 779-789. , 26093923 4509710; Bodi, V., Monmeneu, J.V., Ortiz-Perez, J.T., Lopez-Lereu, M.P., Bonanad, C., Husser, O., Minana, G., Forteza, M.J., Prediction of reverse remodeling at cardiac MR imaging soon after first ST-segment-elevation myocardial infarction: Results of a large prospective registry (2016) Radiology, 278, pp. 54-63. , 26348232; Larose, E., Rodes-Cabau, J., Pibarot, P., Rinfret, S., Proulx, G., Nguyen, C.M., Dery, J.P., Noel, B., Predicting late myocardial recovery and outcomes in the early hours of ST-segment elevation myocardial infarction traditional measures compared with microvascular obstruction, salvaged myocardium, and necrosis characteristics by cardiovascular magnetic resonance (2010) J Am Coll Cardiol, 55, pp. 2459-2469. , 20510213; Cheong, B.Y., Muthupillai, R., Wilson, J.M., Sung, A., Huber, S., Amin, S., Elayda, M.A., Flamm, S.D., Prognostic significance of delayed-enhancement magnetic resonance imaging: Survival of 857 patients with and without left ventricular dysfunction (2009) Circulation, 120, pp. 2069-2076. , 19901193; Ludman, A.J., Yellon, D.M., Hasleton, J., Ariti, C., Babu, G.G., Boston-Griffiths, E., Venugopal, V., Swanton, H., Effect of erythropoietin as an adjunct to primary percutaneous coronary intervention: A randomised controlled clinical trial (2011) Heart, 97, pp. 1560-1565. , 1:CAS:528:DC%2BC3MXhtlKjtb3M 21900585; Crimi, G., Pica, S., Raineri, C., Bramucci, E., De Ferrari, G.M., Klersy, C., Ferlini, M., Romeo, M., Remote ischemic post-conditioning of the lower limb during primary percutaneous coronary intervention safely reduces enzymatic infarct size in anterior myocardial infarction: A randomized controlled trial (2013) JACC Cardiovasc Interv, 6, pp. 1055-1063. , 24156966; Bulluck, H., White, S.K., Frohlich, G.M., Casson, S.G., O'Meara, C., Newton, A., Nicholas, J., Sirker, A., Quantifying the area at risk in reperfused ST-segment-elevation myocardial infarction patients using hybrid cardiac positron emission tomography-magnetic resonance imaging (2016) Circ Cardiovasc Imaging, 9, p. e003900. , 26926269 4826603; Bulluck, H., Rosmini, S., Abdel-Gadir, A., White, S.K., Bhuva, A.N., Treibel, T.A., Fontana, M., Ramlall, M., Automated extracellular volume fraction mapping provides insights into the pathophysiology of left ventricular remodeling post-reperfused ST-elevation myocardial infarction (2016) J Am Heart Assoc, 5, p. e003555. , 27402229 5015393; Bulluck, H., Rosmini, S., Abdel-Gadir, A., Bhuva, A.N., Treibel, T.A., Fontana, M., Weinmann, S., Manisty, C., Impact of microvascular obstruction on semiautomated techniques for quantifying acute and chronic myocardial infarction by cardiovascular magnetic resonance (2016) Open Heart, 3, p. e000535. , 28008358 5174824; Bulluck, H., Rosmini, S., Abdel-Gadir, A., White, S.K., Bhuva, A.N., Treibel, T.A., Fontana, M., Sirker, A., Residual Myocardial Iron Following Intramyocardial Hemorrhage During the Convalescent Phase of Reperfused ST-Segment-Elevation Myocardial Infarction and Adverse Left Ventricular Remodeling (2016) Circ Cardiovasc Imaging., 9. , e004940 27894068 5068185; Thavendiranathan, P., Grant, A.D., Negishi, T., Plana, J.C., Popovic, Z.B., Marwick, T.H., Reproducibility of echocardiographic techniques for sequential assessment of left ventricular ejection fraction and volumes: Application to patients undergoing cancer chemotherapy (2013) J Am Coll Cardiol, 61, pp. 77-84. , 23199515; Chuang, M.L., Gona, P., Hautvast, G.L., Salton, C.J., Blease, S.J., Yeon, S.B., Breeuwer, M., Manning, W.J., Correlation of trabeculae and papillary muscles with clinical and cardiac characteristics and impact on CMR measures of LV anatomy and function (2012) JACC Cardiovasc Imaging, 5, pp. 1115-1123. , 23153911 3502069; Weinsaft, J.W., Cham, M.D., Janik, M., Min, J.K., Henschke, C.I., Yankelevitz, D.F., Devereux, R.B., Left ventricular papillary muscles and trabeculae are significant determinants of cardiac MRI volumetric measurements: Effects on clinical standards in patients with advanced systolic dysfunction (2008) Int J Cardiol, 126, pp. 359-365. , 17698216; Kozor, R., Callaghan, F., Tchan, M., Hamilton-Craig, C., Figtree, G.A., Grieve, S.M., A disproportionate contribution of papillary muscles and trabeculations to total left ventricular mass makes choice of cardiovascular magnetic resonance analysis technique critical in Fabry disease (2015) J Cardiovasc Magn Reson, 17, p. 22. , 25890002 4335368; Orn, S., Manhenke, C., Greve, O.J., Larsen, A.I., Bonarjee, V.V., Edvardsen, T., Dickstein, K., Microvascular obstruction is a major determinant of infarct healing and subsequent left ventricular remodelling following primary percutaneous coronary intervention (2009) Eur Heart J, 30, pp. 1978-1985. , 19502624; Hamirani, Y.S., Wong, A., Kramer, C.M., Salerno, M., Effect of microvascular obstruction and intramyocardial hemorrhage by CMR on LV remodeling and outcomes after myocardial infarction: A systematic review and meta-analysis (2014) JACC Cardiovasc Imaging, 7, pp. 940-952. , 25212800 4301583

PY - 2017

Y1 - 2017

N2 - Background: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. Methods: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined. Secondly, in 146 reperfused STEMI patients, receiver operator characteristic curve analyses for predicting LVEF

AB - Background: The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR criteria for assessing LV remodeling following acute MI. Methods: Firstly, 40 reperfused ST-segment elevation myocardial infarction (STEMI) patients with paired acute (4 ± 2 days) and follow-up (5 ± 2 months) CMR scans were analyzed by 2 independent reviewers and the minimal detectable changes (MDCs) for percentage change in LV end-diastolic volume (%ΔLVEDV), LV end-systolic volume (%ΔLVESV), and LV ejection fraction (%ΔLVEF) between the acute and follow-up scans were determined. Secondly, in 146 reperfused STEMI patients, receiver operator characteristic curve analyses for predicting LVEF

KW - infarct size, microvascular obstruction

KW - LV ejection fraction

KW - LV end-diastolic volume

KW - LV end-systolic volume

KW - LV remodeling, trabeculae and papillary muscles

KW - ST-segment elevation myocardial infarction

KW - adult

KW - Article

KW - cardiovascular magnetic resonance

KW - clinical article

KW - female

KW - follow up

KW - heart left ventricle ejection fraction

KW - heart left ventricle enddiastolic volume

KW - heart left ventricle endsystolic volume

KW - heart left ventricle mass

KW - heart muscle reperfusion

KW - heart ventricle remodeling

KW - human

KW - male

KW - observer variation

KW - sensitivity and specificity

KW - ST segment elevation myocardial infarction

KW - aged

KW - area under the curve

KW - cine magnetic resonance imaging

KW - diagnostic imaging

KW - heart left ventricle function

KW - heart stroke volume

KW - middle aged

KW - pathophysiology

KW - percutaneous coronary intervention

KW - predictive value

KW - receiver operating characteristic

KW - reproducibility

KW - time factor

KW - treatment outcome

KW - Aged

KW - Area Under Curve

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging, Cine

KW - Male

KW - Middle Aged

KW - Observer Variation

KW - Percutaneous Coronary Intervention

KW - Predictive Value of Tests

KW - Reproducibility of Results

KW - ROC Curve

KW - ST Elevation Myocardial Infarction

KW - Stroke Volume

KW - Time Factors

KW - Treatment Outcome

KW - Ventricular Function, Left

KW - Ventricular Remodeling

U2 - 10.1186/s12968-017-0343-9

DO - 10.1186/s12968-017-0343-9

M3 - Article

SN - 1097-6647

VL - 19

JO - Journal of Cardiovascular Magnetic Resonance

JF - Journal of Cardiovascular Magnetic Resonance

IS - 1

ER -

Defining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance

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