TY - JOUR
T1 - DEFB1 gene polymorphisms and increased risk of HIV-1 infection in Brazilian children
AU - Milanese, Michele
AU - Segat, Ludovica
AU - Pontillo, Alessandra
AU - Arraes, Luiz Claudio
AU - De Lima Filho, José Luiz
AU - Crovella, Sergio
PY - 2006/8
Y1 - 2006/8
N2 - In our study we analysed three single nucleotide polymorphisms (SNPs) in the 5′ untranslated region (UTR) of the DEFB1 gene, namely -52(G/A) -44(C/G) and -20(G/A), in three groups of northeastern Brazilian children in order to assess their role in HIV-1 infection. Our results allowed us to hypothesize that the SNPs located in the 5′ UTR of the DEFB1 gene can be employed as a marker of risk for HIV-1 infection.
AB - In our study we analysed three single nucleotide polymorphisms (SNPs) in the 5′ untranslated region (UTR) of the DEFB1 gene, namely -52(G/A) -44(C/G) and -20(G/A), in three groups of northeastern Brazilian children in order to assess their role in HIV-1 infection. Our results allowed us to hypothesize that the SNPs located in the 5′ UTR of the DEFB1 gene can be employed as a marker of risk for HIV-1 infection.
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U2 - 10.1097/01.aids.0000238417.05819.40
DO - 10.1097/01.aids.0000238417.05819.40
M3 - Article
C2 - 16868452
AN - SCOPUS:33746768204
SN - 0269-9370
VL - 20
SP - 1673
EP - 1675
JO - AIDS
JF - AIDS
IS - 12
ER -