TY - JOUR
T1 - Daily Functioning in Schizophrenia
T2 - Is There Room for Anxiety?
AU - Buonocore, Mariachiara
AU - Bosinelli, Francesca
AU - Bechi, Margherita
AU - Spangaro, Marco
AU - Cocchi, Federica
AU - Bianchi, Laura
AU - Guglielmino, Carmelo
AU - Baraldi, Maria Alice
AU - Anchora, Lavinia
AU - Bringheli, Serena
AU - Cavallaro, Roberto
AU - Bosia, Marta
PY - 2019/1/1
Y1 - 2019/1/1
N2 - The present study aims at evaluating the impact of anxiety on functional outcome in patients with schizophrenia, also taking into account the other main predictors of functioning identified by literature, to disentangle specific subcomponents which contribute to functional outcome. One hundred five patients with DSM-IV-TR schizophrenia were recruited and underwent a broad functional, psychopathological, and clinical-neuropsychological battery. A forward stepwise regression model was used to assess the predictive effect of anxiety and other factors on daily functioning, showing significant results only for global neurocognitive status and anxiety. These results confirm the role of neurocognition and are also in line with the hypothesis that trait anxiety has a direct impact on functional outcome. Overall, the findings support the role of anxiety as a core feature of schizophrenia pathology, with important implications for both research and clinical settings.
AB - The present study aims at evaluating the impact of anxiety on functional outcome in patients with schizophrenia, also taking into account the other main predictors of functioning identified by literature, to disentangle specific subcomponents which contribute to functional outcome. One hundred five patients with DSM-IV-TR schizophrenia were recruited and underwent a broad functional, psychopathological, and clinical-neuropsychological battery. A forward stepwise regression model was used to assess the predictive effect of anxiety and other factors on daily functioning, showing significant results only for global neurocognitive status and anxiety. These results confirm the role of neurocognition and are also in line with the hypothesis that trait anxiety has a direct impact on functional outcome. Overall, the findings support the role of anxiety as a core feature of schizophrenia pathology, with important implications for both research and clinical settings.
KW - Anxiety
KW - functional outcome
KW - neurocognition
KW - predictor
KW - schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=85070787295&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070787295&partnerID=8YFLogxK
U2 - 10.1097/NMD.0000000000001030
DO - 10.1097/NMD.0000000000001030
M3 - Article
C2 - 31232908
AN - SCOPUS:85070787295
SN - 0022-3018
JO - Journal of Nervous and Mental Disease
JF - Journal of Nervous and Mental Disease
ER -