TY - JOUR
T1 - Current concepts for the diagnosis and management of eosinophilic granuloma of bone
AU - Angelini, Andrea
AU - Mavrogenis, Andreas F.
AU - Rimondi, Eugenio
AU - Rossi, Giuseppe
AU - Ruggieri, Pietro
PY - 2016/10/21
Y1 - 2016/10/21
N2 - This review summarizes current concepts in the diagnosis and management of the patients with eosinophilic granuloma. Given the benign biology, the clinical course, and the pediatric group of patients that this condition more commonly affects, a treatment approach that carries a lower risk of complications while ensuring a successful cure is desirable. Variable treatment options have been reported with satisfactory results and a recurrence rate of less than 20 %. In this setting, symptomatic lesions that are accessible in the spine or the extremities may be treated with intralesional methylprednisolone injection after tissue biopsy for histological diagnosis.
AB - This review summarizes current concepts in the diagnosis and management of the patients with eosinophilic granuloma. Given the benign biology, the clinical course, and the pediatric group of patients that this condition more commonly affects, a treatment approach that carries a lower risk of complications while ensuring a successful cure is desirable. Variable treatment options have been reported with satisfactory results and a recurrence rate of less than 20 %. In this setting, symptomatic lesions that are accessible in the spine or the extremities may be treated with intralesional methylprednisolone injection after tissue biopsy for histological diagnosis.
KW - Bone tumors
KW - Eosinophilic granuloma
KW - Extremities
KW - Methylprednisolone injection
KW - Spine
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U2 - 10.1007/s10195-016-0434-7
DO - 10.1007/s10195-016-0434-7
M3 - Article
AN - SCOPUS:84992027568
SN - 1590-9921
SP - 1
EP - 8
JO - Journal of Orthopaedics and Traumatology
JF - Journal of Orthopaedics and Traumatology
ER -